現有的血袋材料多為聚氯乙烯為主，然而其中卻含有高達45%的塑化劑，對於新生兒或是長期需要換液的病患，可能會有影響生長與生殖的風險。因此目前仍然在找尋可替代材料。
本研究利用陰離子聚合法，成功聚合出聚苯乙烯-異戊二烯-苯乙烯三嵌段共聚物(Poly(Styrene-Isoprene-Styrene)，SIS)，其中苯乙烯鏈段中含有不同比例的苯乙烯和叔丁基苯乙烯(4-tert-butylstyrene)。藉由金屬觸媒的催化，成功氫化SIS中未飽和的雙鍵，得到聚苯乙烯-乙烯-丙烯-苯乙烯(Poly(Styrene-Ethylene-Propylene-Styrene)，SEPS)。之後，將SEPS和聚丙烯(Polypropylene，PP)依不同比例混參。由於SEPS結構與PP相似，這可能提供兩者良好的相容性，並且改善PP的機械性質。最後，利用醋酸酐(Acetic anhydride)與硫酸(Sulfuric acid)將SEPS磺酸化，預計以含有不同比例的叔丁基苯乙烯，獲得不同磺酸化程度的SEPS/PP (sulfonated SEPS/PP，s-SEPS)。
因帶有負電的磺酸根，改善材料的疏水性質；部分磺酸化也保留SEPS的熱彈性質；實驗結果亦顯示此材料無細胞毒性，且有效減少血小板貼附量和變形。具有發展成血袋材料的潛能。本研究將利用各種儀器與方法探討材料的結構、機械性質、親疏水性等物理特性。

Most of modern blood bag is mainly made of polyvinyl chloride (PVC) and plasticizers. However, for newborns or patients who need transfusion for a long time or a huge volume, exposure to plasticizers would be a potential problem of fertility and development. Therefore, these years, experts are still looking for alternative materials for blood bag.
In this study, we successfully synthesized poly(styrene-isoprene-styrene) (SIS) triblock copolymer whose styrene segments contain different ratio of 4-tert-butylstyrene (tBS) with anionic polymerization. Through hydrogenating unsaturated double bonds in SIS, poly(styrene-ethylene-propylene-styrene) (SEPS) was obtained. SEPS was then blended with polypropylene (PP) in different proportions. Since the structure of SEPS is similar to that of PP, this provide a good compatibility and, resulting, an improvement in mechanical properties of PP. Subsequently, the surface of blends was sulfonated with acetic anhydride and sulfuric acid. We expected that we could obtain different degrees of sulfonation of blends (s-SEPS/PP) with controlling different ratio of tBS, and this partial sulfonation could retain the thermoelastic properties of SEPS. Based on various analyses methods, the results would be reported to explore the physical properties and chemical characteristics, such as the chemical configuration, mechanical properties, surface hydrophobicity, and hemocompatibility of different materials prepared.
Finally, after sulfonation treatment, we could get a hemocompatibility material without cytotoxicity. With the negative surface, platelet adhesion and activation could be reduced by s-SEPS/PP blends. Nonetheless, due to little consideration of sulfonated PP and the effect of molecular weight, tuning degree of sulfonated SEPS/PP with different tBS ratio still poses challenges.

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