漫反射光譜學(Diffuse Reflectance Spectroscopy，簡稱DRS)技術，此技術即為一種非侵入式光學量測技術，能夠對人體皮膚組織進行定量分析，提供人們即時的生理資訊做為健康判斷的依據，亦能夠在醫療上作為簡易的診斷以及臨床分析的重要參考指標。由於光子擴散理論的量測距離限制，我們透過蒙地卡羅法建立理論模型數據庫，並訓練人工類神經網路(Artificial Neural Network ，ANN)建立對應的演算法，將我們漫反射光譜量測到的人體光譜計算為吸收係數(absorption coefficient,μ_a)與散射係數(scattering coefficient,μ_s)，在將吸收係數透過光譜擬和出人體的血紅素數質。
血液循環在人體中有兩個主要的功能，一是提供身體皮膚組織所需要的營養素並帶走代謝後的產物，二是調節運動中所產生的皮膚溫度變化來進行散熱的功能以調節身體的溫度，因此若能在運動中透過微型化穿戴式光學量測系統監控血紅素這項數質變化及可分析出人體在運動中所發生的各種生理現象來對當次運動進行分析，便能提高運動訓練的效率。
本研究主要分為兩部分，首先將原先實驗室所使用的大型精密平台是量測系統進行微型化，並改良為穿戴式量測系統，透過仿人體之假體與人體驗證此穿戴式裝置的可行性，並與精密平台是做比較，顯示在血紅素以及黑色素的量測結果中趨勢相同。最後於實驗室內進行漸增性負荷運動並透過穿戴式裝置觀察受測者的血紅素變化，從中解釋合理的量測到其血液根據運動生理的變化進而分析出高校的燃脂區間。

In this study, we use a miniature spectrometer (C12880MA), a 400-600nm LED light source and spatially resolved diffuse reflectance spectroscopy (SRDRS) to development a noninvasive wearable measuring instrument with the novel spectral analysis algorithm in order to measure and calculate the optical parameters of the skin. In the spectrum we analyzed, the main chromophores in human skin are oxyhemoglobin, hemoglobin and melanin. First, we verify the feasibility of the algorithm on DRS wearable system when doing calibration on two phantom and compare it with the laboratory's complete measurement system. The results show that the algorithm is work on both system. The second part, we measured 4 position on human skin. The results show that the trend of hemoglobin and melanin is same between laboratory's complete measurement system and DRS wearable system. Final, we measured 6 subject’s hemoglobin by doing incremental exercise. Find the correlation between human skin hemoglobin and skin temperature, also monitoring heart rate and muscle hemoglobin during exercise. The results show that skin hemoglobin have high correlation with skin thermoregulation, and skin hemoglobin is also affected by heart rate and skin vasoconstriction with other circulatory adjustments to maintain muscle perfusion.

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