一種結合生物科技與製藥產業之新興的營運模式正在形成，即利用生物科技中的重組基因方式用於製藥過程之重新設計，可大幅改善目前藥廠以化學製藥之副作用與高成本，並能使藥效更符合病患所需。本研究探討如何架構此一新興產業之營運模式為思考主軸，並創新架構出讓生物科技與製藥產業可以參考依循的「生技專業藥廠營運模式」，再選取南科園區中的一家生技專業藥廠為個案研究對象，透過個案公司高階經理人的深入訪談，配合蒐集國內外生技專業藥廠有關的資訊及次級資料分析，以利個案企業在競爭優勢上的發展，並回饋幫助此創新營運模式的建構與確認。
創新之「生技專業藥廠之PRFRAC營運模式」，以六大結構並細分十二區塊組成，包括：產品（價值主張、市場區隔）；研發（法規、技術來源）；財務（成本結構、收入模型）；資源（設備、經營結構）；聯盟（合作、相互關係）；顧客（目標顧客、經銷管道）等，試圖架構生技專業藥廠之營運模式並達到競爭優勢，讓業界參考並呈現另一種策略思維，希望讓個案公司與其他相關公司，能有系統、明確、長期性的規劃，無論是所開發之生技藥品能因技術門檻較高與智財權申請而受到保障，或是生技專業藥廠獲利模式獲得投資市場中投資人的青睞，成為全球生技創投業的投資焦點而獲得極高利益。並以生技專業藥廠之PRFRAC營運模式分析此個案公司為，提出營運之適當建議，最終目的達到充分發揮公司自身的核心競爭力、降低經營風險、同時減少資本支出，使公司賺取比競爭對手更高的利潤，可創造無與倫比之市場利基。

關鍵字： 營運模式、生技專業藥廠、生物科技、製藥產業

There is a kind of new business model which can combine biotechnology industry and drug industry. Utilize recombinant DNA technology to redesign the process of drug production. Improve the chemical pharmacy factory more efficiency and avoid side effect and expensive of drug. In this research we create a new business model, and construct 12 operation items of this new biotech specialty pharmacy. Then choose one pharmaceutical company which build in Science Park, and depth interview with company's manager to get company intact operation situation. As several of the major pharmaceutical companies struggle through a period of a relative dearth of big, new products, the job casualties and the share buybacks are piling up this earnings season. We collect domestic and foreign biotechnology industry information to develop and analyze competition advantage of this innovative business model and case enterprise.
Innovation of the PRFRAC business model analysis for biotech specialty pharmacy, which has six major structure including : Product（Value Proposition, Market Segmentation）；Research（Regulations, Technology Resource）；Finance（Cost Structure, Revenue Model）；Resource（Capability, Structure）；Alliance（Partnership, Relationship）；and Customer（Target Customer, Distribution Channel）. Hope to present another view of strategy and competition advantage. No matter the new medicines can apply to ownership of property intelligently, or create the profit-making way of pharmaceutical factory and get investors' favor in the investment market. The final purpose of analysis in PRFRAC business model, we want to reduce the business risk, achieve company worthy, and create the unparalleled market niche.

Key words：business model, biotech specialty pharmacy, biotechnology, pharmacy industry.

中文文獻
1. 榮泰生，”企業研究方法”，台北：五南，1997年。
2. 王玉民，”社會科學研究方法原理”，台北：洪葉文化，1994年。
3. 經濟部，生物技術產業年鑑-2004，財團法人生物技術開發中心，民94年。
4. 經濟部，生物技術產業年鑑-2005，財團法人生物技術開發中心，民95年。
5. 經濟部，生物技術產業年鑑-2006，財團法人生物技術開發中心，民96年。

英文文獻
1. Alicia Loffler (2002)，“Trends in biotechnology：Implications for the pharmaceutical industry”，International Journal of Medical Marketing，Vol.2，No. 4，pp.345-348。
2. Afuah A. N.and Tucci C.L., (2003) “Internet Business Model and Strategies: Text and Cases”,chap.6, McGraw-Hill, New York
3. Applegate, L.M. and M. Collura. “Amazon.com, 2000.” Harvard Business School Case No. 801-194, Sep. 2001.
4. Arojarvi and Olli（2001）〝How to value a biotechnology firms：A study of Current Approaches and Key Value Drivers〞，Helsinki School of Economics and Business Administration。
5. Chesbrough, H. and R.S. Rosenbloom. (2002).“The Role of the Business Model in Capturing Value from Innovation,” Industrial and Corporate Change, 11(3), pp.529-556.
6. Chesbrough, H. and R.S. Rosenbloom. “The Role of the Business Model in Capturing Value from Innovation: Evidence From Xerox Corporation's Technology Spinoff Companies.” Harvard Business School, Division of Research, no. 01-002,July 2000.
7. Dubosson-Torbay, M., A. Osterwalder, and Y. Pigneur. “E-Business Model Design,Classification, and Measurements.” Thunderbird International Business Review, vol.44, no. 1, Jan.-Feb. 2002, pp.5-23.
8. Ernst & Young. Global investment in 2002. Avaiable from URL: http://www.ey.com/global/Content.nsf/International.htm
9. KMLab, Inc. “Business Model Warfare.” http://www.kmlab.com/4Gwarfare.html,2000.
10. Mahadevan, B. “Business Models for Internet-Based E-Commerce: An Anatomy.”California Management Review, vol. 42, no. 4, Summer 2000, pp.55-69.
11. Merriam, S B. (1988), Case Study Research in Education: A qualitative approach. San Francisco: Jossey-Bass.
12. Peterovic, O., C. Kittl, et al. (2001). Developing Business Models for eBusiness. International Conference on Electronic Commerce 2001, Vienna.
13. Rappa, M. “Managing the Digital Enterprise: Business Models on the Web.”http://digitalenterprise.org/models/models.html, 2000.
14. Rappa, M.. Business models on the Web.Managing The Digital Enterprise. [Online].Available:http://digitalenterprise.org/models/models.html, 2003.
15. Roberts, E. B. and Mizouchi, R.,‘Inter-firm Technological Collaboration : The Case of Japanese Biotechnology’,International Journal of Technology Management,Vol.4(1),1989 pp.43-61.
16. Rodney M. Thomas BSc, FCA, (2000), “An Idiot’s Guide to E-commerce”,Information Management & Technology, Vol. 33, No. 2, pp. 69-71
17. Spalding, B. J.,‘How Biotechnology is Farming as a Industry’,Chemical Week, Vol.139(23), ，1986 pp.9-13.
18. Timmers, P. “Business Models for Electronic Markets.” Journal on Electronic Markets, vol. 8, no. 2, Apr. 1998, pp.3-8.
19. Timmers, P. (1999). Electronic Commerce: Strategies and Models for Business-to-Business Trading. Chichester, John Wiley & Sons Ltd.
20. Venkatraman and Ramanujam（1986） “Modeling the Effectiveness of a Strategic Planning System” ， Lamb,-Robert, ed; Shrivastava,-Paul, ed; Advances in strategic management. Volume 5.. A Research Annual. Greenwich, Conn. and London: JAI Press ，PP.113-38
21. Weill, P. and M. R. Vitale (2001). Place to space: Migrating to eBusiness Models. Boston, Harvard Business School Press.
22. Yin, R.K, Bateman, PG., & Moore, G.B. (1983), Case Studies and Organizational Innovation: Strengthening the connection. COSMOS Corporation.
23. Yin R.K. (1994),Case Study Research, Design and Methods, 2nd ed. Newbury Park, Sage Publications.