本研究第一部分為以同步小角/廣角X光散射實驗研究不同溫度下PNIPAM水溶液之微結構變化，首先將SAXS與WAXD強度分布重疊後，將WAXD強度分布以兩個Lorentzian functions作擬合後，將此強度分布從SAXS強度分布中扣除後，從其Iq2對q做圖中發現當溫度上升，q= 0~0.1 Å-1處有一明顯之峰且溫度上升強度愈強，無法只以OZ function作擬合，故引入sphere scattering與OZ function擬合SAXS強度分布[扣除WAXD強度分布]。

第二部分為以低溫電紡設備，藉由將溶液溫度控制在低於相分離溫度來製備PNIPAM奈米纖維。探討改變溶液溫度、工作距離與濃度對電紡過程及產物影響，以CCD及高速攝影機觀察電紡過程，SEM、TEM、POM觀察產物。

In the first part of this study, we use a synchrotron small- and wide-angle x-ray scattering (SAXS/WAXD) to investigate the variation of microstructures of poly(N-isopropyl acrylamide) (PNIPAM) aqueous solutions at different temperature. First, we overlapped the SAXS and WAXD intensity profiles. The SAXS intensity profile subtracted the model, which was used to describe WAXD intensity profiles by two Lorentzian functions. From Iq2 -q plot, we found that there was an obvious peak appealing at q= 0~0.1 Å-1 when the temperature increased, which the SAXS intensity profile subtracting the model cannot be described by only a OZ function; therefore, the SAXS intensity profile subtracting the model was described by sphere scattering and OZ function.

In the second part, the electrospinning was performed at the different solution temperature and concentration how the electrospinning process recorded by the CCD, digital camera and high speed camera and electrospun fibers observed under a scanning electron microscope (SEM), transmission electron microscope (TEM) and polarized optical microscopy (POM) were influenced.

[1] H. Schnablegger, Y. Singh, The SAXS Guide, Anton Paar GmbH, (2011)
[2] J. Als-Nielsen, D. McMorrow, Elements of Modern X-ray Physics, John Wiley & Sons Ltd, (2001)
[3] K. Otake, H. Inomats, M. Konno, S. Saito, “Thermal Analysis of the Volume Phase Transition with N-Isopropylacrylamide Gels.” Macromolecules, 23, 283-289 (1990).
[4] I. Ando, S. Fujishige, K. Kubota, “Phase transition of aqueous solutions of poly(N-isopropylacrylamide) and poly(N-isoproylmethacrylamide).” The Journal of Physical Chemistry, 93, 8, 3311 (1989).
[5] H.G.SCHILD,“Poly(N-isoproylacrylamide): experiment, theory and application.” Progress in Polymer Science, 17, 163(1992).
[6] M. Shibayama, T. Tanaka, C. C. Han, “Small angle neutron scattering study on poly(N‐isopropyl acrylamide) gels near their volume‐phase transition temperature.” The Journal of Chemical Physics, 97, 6829-6841 (1992).
[7] A. Meier-Koll, V. Pipich, P. Busch, C. M. Papadakis, P. Muller-Buschbaum, “Phase Separation in Semidilute Aqueous
Poly(N-isopropylacrylamide) Solutions.” Langmuir, 28, 8791-8798 (2012).
[8] K. Yanase, R. Buchner, T. Sato, “Microglobule formation and a microscopic order parameter monitoring the phase transition of aqueous poly(N-isopropylacrylamide) solution.” Physical Review Materials, 2, 8 (2018).
[9] H. Inomata, Y. Yagi, K. Otake, M. Konno, S. Saito, “Spinodal Decomposition of an Aqueous Solution of Poly(N-isopropylacrylamide).” Macromolecules, 22, 3494-3495 (1989).
[10] Y. Wang, T. Hashimoto, C. C. Li, Y. C. Li, C. Wang, “Extension Rate of the Straight Jet in Electrospinning of Poly(N-isopropyl acrylamide) Solutions in Dimethylformamide: Influences of Flow Rate and Applied Voltage.” Journal of Polymer Science Part B-Polymer Physics, 56, 319-329 (2018).
[11] A. Holzmeister, A. L. Yarin, J. H. Wendorff, “Barb formation in electrospinning: Experimental and theoretical investigations.” Polymer, 51, 2769(2010).
[12] C. A. Dreiss, K. S. Jack, A. P. Parker, “On the absolute calibration of bench-top small-angle X-ray scattering instruments: a comparison of different standard methods." Journal of Applied Crystallography, 39, 32-38 (2006).
[13] 莊亞臻, “電紡聚(異丙基丙烯醯胺)水溶液.” 國立成功大學碩士論文 (2015).