靜電紡絲是近年來用來製備多功能性高分子奈米纖維的一項新穎技術。多功能性高分子溶液被電場吸引到噴嘴下方幾英吋距離的目標物表面，噴出的聚合物經延展後而變為奈米級纖維。當考量製備感測元件的應用價值時，相較於微米等級的纖維，電紡纖維因大幅度的提高纖維的比表面積，進而提升感測能力。本論文利用施蒂勒耦合反應（stille coupling reaction）與鈴木-宮浦耦合反應（ Suzuki-Miyauracoupling　reaction）合成具金屬離子感測能力的分子Bpy-F-Bpy與單體Fbpy。配合N-methylolacrylamide (NMA)作為奈米纖維的交聯鏈段，以及具有溫度敏感性質的N-isopropylacrylamide (NIPAAm)作為協助纖維再生的脫水(dehydration)鏈段，以自由基聚合法（Free Radical polymerization）合成不同比例的共聚高分子 poly(NIPAAm-co-NMA)與 poly(NIPAAm-co-NMA-co-Fbpy)。將前者混摻螢光感測基團 Bpy-F-Bpy後以靜電紡絲技術製備為高分子奈米纖維與由後者製備出的高分子靜電紡絲纖維分別作為金屬離子感測器，針對其奈米結構、金屬離子感測和光物理性質進行研究。
我們發現能透過改變NMA之混摻比例調整鏈段的親水性，調整其最低臨界溶解溫度(lower critical solution temperature，LCST)；透過改變Bpy-F-Bpy摻混比例調整奈米纖維對金屬離子的感測能力。當Bpy-F-Bpy分別為溶液、混摻薄膜、混摻奈米纖維型態進行Hg2+感測時，可發現奈米纖維之Stern-Volmer plot之斜率的絕對值較大且螢光光譜紅移(red shift)較薄膜與溶液明顯。因為溶液類似三維結構、薄膜比較類似二維結構，而fiber因為纖維的侷限性而較類似一維結構。而較紅移代表聚集程度較好，斜率較大代表敏感程度較好，因此利用價值以纖維較勝於薄膜。我們將螯合過金屬離子之纖維加熱高於LCST導致纖維脫水，而脫水使金屬離子脫附，達到再生的目的。

Two series of multifunctional electrospun (ES) nanofibers composed of poly(NIPAAm-co-NMA) blending BpyFBpy and poly(NIPAAm-co-NMA-co-Fbpy), respectively, were successfully prepared via the ES process. FBPY demonstrated blue or red shift in emission wavelength and intensity quench when chelation with different metal ions. With appropriate proportion of NMA in the copolymers, films and nanofibers can maintain their morphology in water with varying temperature treatments. Copolymers in three states, solution, film and nanofiber, were prepared and their effects on sensing ability were investigated.

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