釩金屬於生物系統中所扮演的角色十分重要，因此一直是很有趣一門研究課題，像是含釩固氮酵素、釩鹵素過氧化酵素、抑制酪氨酸磷酸化酵素及由毒蝿傘(Amantia muscaria) 體中分離出來的amavadin都是跟釩化學相關的。在海鞘生物體中也發現有累積高濃度的釩三價化合物。此外，有些釩化合物被發現具有類胰島素的性質。為了探討在這些生物系統中釩化合物的化學特性，因此我們實驗室著重於釩化學的研究，論文的第一部分是討論藉由循環伏安法(Cyclic voltammetry，CV)的測定，以了解我們實驗室已合成的含硫釩化合物之氧化還原性質，而這些含硫釩化合物分別為[PPh4][VIII(PS3’)Cl] (1)、[PPh4][VIII(PS3”)Cl] (2)、[VIII(PS3”)(N2H4)3] (3)、[NPr4][VIII(PS3)N3] (4)、[VIV(P2S4’)] (5)及[NEt4][VIV(PS3’)(PS2SMe’)] (6)。其中2在以CH3CN為溶劑、CoCp2為還原劑及以2,6-lutidinium chloride供給氫離子的條件下，可以將N2H4催化還原成NH3。因此藉由循環伏安法的測定而釐清此催化還原的反應機制。在第二部份的研究是使用高頻率高磁場電子自旋共振(High-frequency and -Field Electronic Paramagnetic Resonance，HFEPR)光譜儀測定化合物Na[VIII(edta)(H2O)]•3H2O (7), Na[VIII(trdta)]•3H2O (8), [VIII(nta)(H2O)3] (9)，用來了解釩三價化合物在水溶液條件下的HFEPR光譜性質，未來可以用於釐清海鞘生物體中的釩化合物是以怎麼樣的形式所儲存，然而此方面的研究是與美國Krzystek與Telser博士合作所測得的HFEPR光譜。
本論文將詳細介紹化合物1~6的電化學性質及文獻比較，以及7~9的HFEPR光譜性質及文獻討論。

There has been an increasing interest in the study of vanadium chemistry due to the importance of vanadium in biological systems. For instance, vanadium plays the key role in vanadium nitrogenase and haloperxoidases, the inhibits protein tyrosine phosphatase (PTP), and is found in amavadin from Amantia muscaria. Ascidians also contain high concentration of vanadium(III) species in their blood cells. In addition, some vanadium complexes have insulin-mimetic behavior. Because of these observations, our laboratory has been focusing on chemistry of vanadium species, particularly, reacting with S-donor ligands such as thiolates. We have obtained a series of vanadium-thiolate complexes including [PPh4][VIII(PS3’)Cl] (1), [PPh4][VIII(PS3”)Cl] (2), [VIII(PS3”)(N2H4)3] (3), [NPr4][VIII(PS3)N3] (4), [VIV(P2S4’)] (5), and [NEt4][VIV(PS3’)(PS2SMe’)] (6). In the first part of my research, the cyclic voltametry was applied for the study of these compounds to reveral their redox properties that might provide mechanistic understanding for their reactivity. Especially, hydrazine could be catalytically reduced to ammonia by 2 under CH3CN, while the CoCp2 and 2,6-lutidinium chloride as electron sources and proton sources, respectively. Due to cyclic voltammeter, the mechanism of catalytic reduction could be clearer. In the second part of my research, High-frequency and -Field Electronic Paramagnetic Resonance (HFEPR) spectroscopies of Na[VIII(edta)(H2O)]•3H2O (7), Na[VIII(trdta)]•3H2O (8), [VIII(nta)(H2O)3] (9) were studies to provide spectroscopic features of V(III) species in aqueous solution. This part of the research is collaborating with Prof. Krzystek at Florida State University and Prof. Telser at Roosevelt University in USA.
In this dissertation, we will detail the redox chemistry of 1~6, and the HFEPR spectroscopies of 7~9.

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