本研究嘗試將震波應用於破壞脂肪細胞上，震波聚焦時的空蝕效應可以破壞深層脂肪細胞而破壞，被破壞的脂肪細胞隨人體之新陳代謝消失後使得體重下降。在臨床實驗前，建立一組脂肪假體模型，其物理性質與真實脂肪組織相似，並且施以不同震波能量強度及不同震波次數於該脂肪假體上，而後觀察該脂肪假體所受之破壞程度、損傷範圍及楊氏係數之改變，另外使用壓力探針量測震波焦點之壓力值，經由示波器擷取實驗數據，將實驗數據輸入電腦，以積分程式計算在不同厚度時震波施打於凝膠假體所受之能量強度，並且比較其耗損率，以作為未來動物實驗和臨床上的參考依據。
凝膠假體組織在操作電壓9 kV(3.61 mJ/ mm2，電極間距0.5mm）下，假體組織因震波能量之施打，其楊氏模數的值隨施打次數從1000增加至5000次而改變，由5.63 % 改變增加到27.55 % ，此楊氏模數值的改變代表該組織因震波施打後有軟化的趨勢。由量測震波之能量強度得知，當在9 kV（0.734mJ/mm2，電極間距0.8mm）時，隨凝膠假體組織的厚度由1cm增加到5cm，所耗損的能量為 0.78% 增加到 2.22%。

This study is to try to evaluate the performance of shock-wave lipotripsy on gelatins that emulated animal fats as lithotripsy for kidney stones or orthotripsy for musculo-skeletal disorders. A gelatin was made of jelly powder and water, whose physical property of sound impedance is similar to a true adipose tissue of human being. An experiment was set up for studying the damage effect of different intensities and numbers of shock waves on the gelatin by observing the destruction degree and the change of Young’s modulus. The measured pressure profiles at the second focus by using a PCB pressure sensor are collected through an oscilloscope and are evaluated for losses in the energy flux intensity by an integrating program for different thicknesses of gelatin. These data may be used as a basis of reference for animal or clinical experiments.
It is found that at the operating voltage of 9kV (3.61 mJ/mm2, initial gap 0.5mm), the change in Young’s modulus of the treated gelatin after shock wave treatment is increased from 5.63% to 27.55% as the number of shock waves is increased from 1000 to 5000. The change in Young’s modulus denotes that the treated tissue has a tendency of softening. While the operation voltage is set at 9kV (0.734mJ/mm2, initial gap 0.8mm), the loss in energy flux intensity is increased from 0.78% to 2.22% as the thickness of gelatin is increased form 1cm to 5cm.

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