珊瑚碎屑作為一種潔淨的生物鈣資源，卻因為堆積而成為沿海地區十分困擾的議題，本研究的主要目的即爲解決此一環境問題。
珊瑚碎屑主要由碳酸鈣組成，本研究先將珊瑚碎屑經過前處理，接著是一系列的純化與改質，製備出霰石和球霰石兩種碳酸鈣常見的介穩態晶相。
在製備霰石晶相時，發現溫度和過飽和度會對碳酸鈣整體的晶相比例產生影響。霰石傾向於在 50℃以上且過飽和度較低的環境下生成，本研究發現在70℃、反應 120 分鐘及 450rpm 的攪拌速度下，可合成出霰石比例最高的碳酸鈣晶體，經 XRD 數據計算過後，得到霰石佔比高達 99.1%。這樣的結果已經可媲美以 Mg2+離子合成霰石之技術 ，且其純度、白度及鹽酸不容物分析結果皆符合工業標準。
在製備球霰石晶相時，因為此晶相的不穩定性，其粒徑與晶相比例容易受到環境變化影響。本實驗將碳酸鈉溶液(Na2CO3)加入到氯化鈣溶液(CaCl2)中、轉速 1150rpm、85%乙二醇、反應 60 分鐘、鹽類濃度比為 1M 氯化鈣與 0.05M碳酸鈉及 4ml 反應容量，成功合成出平均粒徑為 337nm 之球霰石晶體，並使用螢光光譜儀計算出其標記藥物之承載容量達 9.6wt.%，高於使用商用藥物載體——微脂體(liposome)承載相同標記藥物之容量，證明球霰石可作為合格的藥物載體，且有商業化之可能性。

This research is dedicated to solving the issues resulting from “coral remains,” a clean and potential bio-calcium carbonate resource in Penghu. One of the most important objectives of this research is to develop technology for recovering coral remains. We used coral remains to synthesize two metastable phases of CaCO3: aragonite and vaterite. Therefore, this research was divided into two sections, synthesis of aragonite and vaterite.
In the aragonite synthesis section, we obtained high-purity aragonite up to 99.1% with an aspect ratio of 14.21 using a novel method. Furthermore, no other chemical additives were involved in this section, which reduced the use of chemicals and costs.
In the vaterite synthesis section, the average size of vaterite particles was only 337nm, which was smaller than most of the research. We also conducted drug loading experiments and achieved a loading capacity of 9.6wt.% by loading the labeling drug TRITC-Dextran into CaCO3 carriers, which outperformed similar research.
In this study, we synthesized high-quality aragonite and vaterite from coral remains, indicating that coral remains is a promising raw material for many industries.

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