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研究生: 陳建維
Chen, Chien-Wei
論文名稱: 耳鳴窄頻雜訊產生器的設計研發
The Design and Development of Narrow-band Noise Generator for Tinnitus
指導教授: 鍾高基
Chung, Kao-Chi
學位類別: 碩士
Master
系所名稱: 工學院 - 醫學工程研究所
Institute of Biomedical Engineering
論文出版年: 2006
畢業學年度: 94
語文別: 中文
論文頁數: 72
中文關鍵詞: 窄頻耳鳴
外文關鍵詞: narrow-band, tinnitus
相關次數: 點閱:72下載:2
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  •   耳鳴患者約佔英國及美國的總人口數的17%;而且耳鳴病患會隨著年齡的增加而增多,在65歲以上的老年人口中耳鳴人數也大約有30%,嚴重的耳鳴噪音有時會影響到正常的生活。目前市面上的耳鳴治療器價格昂貴而且多以寬頻雜訊做為治療音源,卻忽略不同患者之間耳鳴狀況的差異以及了有超過七成的耳鳴患者同時有合併聽力損失的問題。長期配戴對患者正常聽覺往往會造成不必要的傷害。
      根據耳鳴遮蔽法及耳鳴減敏療法的理念,本研究發展建構一窄頻耳鳴雜訊產生平台,提供耳鳴病患特定頻段及特定音量的聲音治療,讓此本土化科技輔具能改善目前一般耳鳴寬頻治療器的缺點。
      本系統軟硬體使用PC、頭戴式耳機、以MSP430F169微處理晶片為主的Dlr169電子模擬板、FLASH Emulation Tool軟體發展工具。應用數位訊號處理以軟體技術撰寫產生亂數值的指令成為寬頻訊號做為系統的白色雜訊,並在晶片中執行FIR濾波演算。以MATLAB的FDATool設計濾波器參數輸入至系統程式,將系統程式燒錄至Dlr169模擬板,再由模擬板進行濾波運算,最後以揚聲器發出雜訊。
      目前本系統已完成初部雛型,本研究針對濾波參數設計時的變數,分析不同阻帶頻寬及階數等多種濾波情況,以輸入及輸出的品質因子差異,判斷合適使用的雜訊以滿足耳鳴患者的需求,並建立系統的音量校正表,其校正結果在可接受的範圍。本研究以耳鳴病患的病例做為驗證資料並與耳鳴測量平台的雜訊做比較,發現本系統具有較佳的效果及實用性。
      本研究未來可朝:1.探討系統所產生的窄頻雜訊對於耳鳴病患的療效, 2.發展俱備窄頻耳鳴聲音治療及助聽復健平台。

     There are 17% of the total population suffering from Tinnitus in UK and USA; the prevalence of tinnitus patients has been increasing with the aging. There are approximately 30% of the elderly population suffering from Tinnitus. The noises from tinnitus have influenced seriously on the daily life for tinnitus patients sometimes. Currently, most of tinnitus devices are to provide wide-band noises for therapeutic purpose, and also expensive. The disadvantages of using wide-band therapeutic noises are: (1) tinnitus patients are suffering from noises with varied frequency bands and intensities; (2) more than 70% of patients also suffering from hearing loss usually at high frequency regions. When tinnitus patients have wear the current wide-band noise device for a period of time, they are usually at high risk of hearing loss. This research, based on the Tinnitus Masking and TRT for patient’s specific frequency band and volume, is to design and develop a microprocessor-based platform to provide customized band-pass noise for the tinnitus. This DSP technique would like to improve the shortcoming of current wide-band noise generator and ultimately be beneficial to the tinnitus.
     This system consists of a PC, Dlr169 emulation board with MSP430F169 chip, earphone, FLASH Emulation Tool for software programming and JTAG transmission line. A wide-band white noise, which is generated through random numbers in PC, is input to the Dlr169 for FIR filter processing. Filter parameters and processing programs, which are designed and programmed through FDATooL of MATLAB, are then down-loaded to the Dlir169. The prescribed narrow-band noise with volume are then output from the speaker.
     The prototype of narrow-band noise platform has been completed. The system calibration has been investigated for different stop bandwidths and rank and volume intensities on optimal parameter design in order to provide high quality narrow-band noises. A comparative study is conducted and the results indicate that the microprocessor-based system provides better narrow-band noise quality than the PC-based platform system.
     A clinical investigation on using the system is suggested in the future.

    目錄 中文摘要………………………………………………………… Ⅰ 英文摘要………………………………………………………… Ⅱ 致謝……………………………………………………………… Ⅲ 目錄……………………………………………………………… Ⅳ 圖目錄…………………………………………………………… Ⅵ 表目錄…………………………………………………………… Ⅸ 第一章 緒論……………………………………………………… 1 1.1 耳鳴盛行率與病因學……………………………………… 1 1.1.1 耳朵解剖構造及聽力生理機轉…………………… 3 1.1.2 耳鳴產生的原因與神經生理……………………… 7 1.2 耳鳴的臨床特徵與治療…………………………………… 9 1.2.1 耳鳴治療方法……………………………………… 13 1.3 耳鳴助聽器科技…………………………………………… 17 1.3.1 噪音產生器之設計原理…………………………… 17 1.3.2 雜訊產生…………………………………………… 17 1.3.3 耳鳴治療雜訊訊號處理之數位式濾波器設計…… 23 1.4 研究動機、目的及特定目標……………………………… 34 1.5 研究假說與重要性………………………………………… 34 第二章 系統設計與材料方法………………………………… 36 2.1 系統設計理念及雜訊產生原理…………………………… 36 2.2 系統設計架構……………………………………………… 39 2.2.1 Dlr169電子模擬板及微控制器msp430晶片功能… 40 2.3 發展環境與軟體工具……………………………………… 48 2.4 耳鳴窄頻雜訊產生器濾波器輸出頻率及音量響應……… 51 2.5 系統雜訊與耳鳴測量平台雜訊之比較…………………… 53 第三章 結果與討論……………………………………………… 55 3.1 耳鳴窄頻雜訊產生器系統雛型…………………………… 55 3.2 濾波參數產生與白色雜訊產生…………………………… 57 3.3 帶通濾波器的響應………………………………………… 59 3.3.1 頻率分析………………………………………………… 59 3.3.2 音量校正………………………………………………… 64 3.4 系統臨床驗證結果………………………………………… 65 第四章 結論與未來展望………………………………………… 70 4.1 結論………………………………………………………… 70 4.2 未來展望…………………………………………………… 70 參考文獻………………………………………………………… 71

    1.蕭雅文,聽力學導論,五南,1997
    2.羅華強,訊號處理-MATLAB的應用,全華科技,2003
    3.何中庸,數位訊號處理程式入門,全華科技,2001
    4.吳國樑,程式設計藝術第四板,全華科技,2004
    5.吳賢財,省電型16位元單晶片MSP430入門實務,滄海書局,2003
    6.鄧錦城,8051語言寶典,亦眾資訊,1993
    7.賴麒文,8051單晶片軔體設計的藝術-軔體建構的思維與解決方 法,文魁資訊,2001
    8.蒙以正,MATLAB入門與精進,儒門圖書,2003
    9.林忠逸,數位訊號處理Digital Signal Processing,麥格羅‧希爾國際,2002
    10.Abraham Shulman, Tinnitus diagnosis/treatment, Lea & Febiger, 1991
    11.Karger, Bernhard Kellerhals and Regula Zogg, Tinnitus Rehabilitation by Retraining, 1999.
    12.Craig S. Petrie, et al., “Anoise-Based IC Random Number Generator” IEEE, 2000.
    13.Coles RRA, “Epidemiology of tinnitus: (1) Prevalence”. J Laryngol Otol, 91 (Suppl.): 7-15, 1984.
    14.David W. Rees and Simon D. Smith, Living with tinnitus, Manchester University, 1991.
    15.Drukier GS, “The prevalence and characteristics of tinnitus with profound sensori-neural hearing impairment”, Am Ann Deaf: 134 260-264, 1989.
    16.Emmanuel C. Ifeachor and Barrie W.Jervis, Digital Signal Processing, Addison-Wesley, 1993.
    17.Eugene N. Bruce, Biomedical Signal Processing and Signal Modeling, John Wiley & Sons, New York, 2001.
    18.Filter Design Toolbox User’s Guide, Version 2, MathWorks, MA, 2002.
    19.Hazell JW, Jastreboff PJ, Tinnitus. I: “Auditory mechanisms: a model for tinnitus and hearing impairment”, J Otolaryngol 19(1): 1-5., 1990.
    20.Http://www.ata.org/. American Tinnitus Association, 2002.
    21.Jastreboff PJ et al. Neurophysiological approach to tinnitus patients, Am.J.Otology 1996; 10:464-472.
    22.Jastreboff PJ et al. Optimal sound use in TRT-theory and practice. Proceedings of Sixth International Tinniuts Seminar, Cambridge, UK. London, UK, 1999.
    23.Jastreboff MM et al. Questionnaires for assessment of the patients and treatment outcome. Proceedings of Sixth International Tinnitus Seminar, , Cambridge, UK. London, UK, 1999.
    24.Jastreboff PJ, Sasaki CT. An animal model of tinnitus: a decade of development; AM J Otol1994; 15(1):19-27.
    25.Kauer JS, Nemitz JW, Sasaki CT. Tinnitus aurium: fact…or fancy. Laryngoscope 1981; 92:1401-1407.
    26.Monson H. Hayes, “Statistical Digital Signal Processing and Modeling”, John Wiley & Sons, New York, 2000.
    27.Richard S. Tyler, Tinnitus Handbook, Singular, 2000.
    28.Sadaoki Furui, Digital Speech Processing, Synthesis, and Recognition, 1989.
    29.Searchfield GD et al. “Digital instruments for tinnitus: mixingpoint identification and threshold-adjusted noise”, Seventh International Tinnitus Seminar, Fremantle, Australia, 2002.
    30.Sheldrake JB et al. Results of tinnitus retraining therapy. Sixth International Tinnitus Seminar, Cambridge, UK, 1999.

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