近年來由於焚化爐興建、工業發展、人們的生活型式，戴奧辛污染已經成為社會大眾關注的環境問題之一，該類化合物造成環境污染之後會經由生物累積及生物濃縮作用進一步產生人體的暴露。有鑑於此，實有必要對本國國民調查人體血液中戴奧辛之背景值資料，研究結果可以提供政府單位重要的基本人體暴露資料，來訂定解決戴奧辛問題的策略。雖然目前有組織、乳汁、血液等人體介質分析可得知血液中多氯戴奧辛/夫喃/擬似戴奧辛之多氯聯苯之濃度。但血液分析則仍是目前評估戴奧辛暴露的最主要及最易進行的方法。因此本研究計畫在搜尋國內有關人體血液中多氯戴奧辛/夫喃/擬似戴奧辛之多氯聯苯調查資料後發現18-25歲年齡層資料仍缺乏，因此本計畫就台灣地區該年齡層青年進行多氯戴奧辛/夫喃/擬似戴奧辛之多氯聯苯背景值調查，以使得台灣地區血液中多氯戴奧辛/夫喃/擬似戴奧辛之多氯聯苯之背景值資料更完整。本研究共完成台灣北、中、南、東六個地區171位青年(男生84位，女生87位)血液中十七種戴奧辛/夫喃濃度及45位青年之十二種擬似戴奧辛之多氯聯苯濃度分析以及相關健康、飲食、時間活動模式問卷之訪視，調查結果171位青年血液中的十七種戴奧辛/夫喃毒性當量濃度範圍6.66-29.8 pg WHO98-TEQDF/g-lipid，平均值為12.4 pg WHO98-TEQDF/g-lipid，標準偏差為3.75 pg WHO98-TEQDF/g-lipid，六個地區以台北地區濃度最高，東部地區濃度最低﹔84位男生濃度範圍7.05-29.8 pg WHO98-TEQDF/g-lipid，平均值為12.5 pg WHO98-TEQDF/g-lipid，標準偏差為4.25 pg WHO98-TEQDF/g-lipid﹔87位女生濃度範圍6.66-22.7 pg WHO98-TEQDF/g-lipid，平均值為12.2 pg WHO98-TEQDF/g-lipid，標準偏差為3.23 pg WHO98-TEQDF/g-lipid，男女濃度沒有統計上之差異。45位青年之十二種擬似戴奧辛之多氯聯苯毒性當量濃度範圍1.19-8.66 pg WHO98-TEQp/g-lipid，平均值為3.94 pg WHO98-TEQp/g-lipid，標準偏差為1.90 pg WHO98-TEQp/g-lipid。以上數值與文獻中曾報導過之紐西蘭(男性12.9，女性12.4 pg WHO-TEQ/g-lipid)、日本(20.7 pg I-TEQDF/g-lipid)、韓國(22.2 pg WHO-TEQ/g-lipid)、台灣同年齡的居民濃度比較，也無特別偏高的情形。
另外由問卷訪視所獲得的青年資料包括各項飲食習慣、健康狀態指標、與血中多氯戴奧辛及夫喃之內在暴露劑量（internal dose）利用統計軟體進行相關統計分析得知，在血液中戴奧辛濃度於不同地區、不同性別、不同生活習慣及飲食習慣特性分纇後之濃度分布情形之相關性統計部分，在居住地(p=0.025)項目六區有統計上明顯差異﹔在青年居住時間、血液中13項生化值、BMI(body mass index)與17種戴奧辛及夫喃濃度(pg-WHO-TEQ/g-lipid)之相關性統計，GLU(血糖) (p=0.026)、GPT（麩丙酮轉胺基酵素）(p=0.042)及ALP（鹼性磷酸酵素）(p=0.022)有明顯統計上的差異﹔另外由六區六校青年平常食用之十大類食物食用總量(主食類、肉類、蔬菜類、魚及海鮮類、內臟類、乳製品、水果、蛋、豆、核果類製品、油脂類、飲料點心類)與血中戴奧辛含量之統計分析部分，攝取之肉類中的牛肉(p=0.013)、乳製品中之全脂牛奶(p=0.006)、油脂類中的豬油(p=0.015)、人造奶油(p=0.001)、蔬菜類中的豆類(p=0.047)與血中戴奧辛有明顯統計上的相關。另外我們將測得的濃度計算六區六校青年的身體負荷量分別為政大174.2、清華164.4、中興175.5、成功189.1、中山179.1、東華125.6 ng。而本研究也依DeVito模式推估六校學生之終生平均暴露量分別為政大1.4、清華1.3、中興1.3、成功1.4、中山1.2、東華1.1 pg WHO-TEQ/kg/day，尚符合世界衛生組織建議之容忍值1-4 pg WHO-TEQ/kg/day，另外六校青年的潛在健康影響風險則分別為政大7×10-4、清華6.5×10-4、中興6.5×10-4、成功7×10-4、中山6×10-4、東華5.5×10-4。

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