自然界中許多複雜的生物結構皆是藉由高度結合的有機物與無機物複合而成，如生物體中的骨骼、牙齒、和海洋中的矽藻、貝類等。本研究將此觀念應用於合成各種型態的奈米材料，利用有機物組成模板，再使無機物凝結於有機體表面上，經過自組合後形成有機－無機複合材料，期盼能合成出與自然界矽藻相似的型態，並提供仿生材料新的合成方法。
本研究中以界面活性劑作為有機模板，再和無機物(四乙氧基矽烷或矽酸鈉溶液)結合得到有機－無機複合材料。由界面活性劑化學可知，在陽性－陰性離子型界面活性劑所組成的混合系統中，可藉由調整兩成分間的比例得到柱狀、球狀和層狀等不同結構的微胞，作為具有特殊型態介尺度結構氧化矽材料的模板，而且兩成份因極性端相反電荷的靜電作用形成類似磷脂質的雙尾鏈兩性物，亦可用於模擬細胞膜性質。本研究採用陽離子型界面活性劑 (CnTMAX，n = 12-18，X = Br或Cl)及陰離子型界面活性劑(SDS)以適當比例混合(SDS/CnTMAB莫耳比，S )作為有機模板，和無機物TEOS在反應pH值3.0，40℃的條件下混合攪拌製備囊泡狀中孔洞氧化矽。
本實驗分成兩個主要部分：一、以C14TMAB為陽離子型界面活性劑所製備之囊泡狀中孔洞氧化矽；二、改變陽離子界面活性劑的碳鏈長以CnTMAB (n = 12, 16, 18)為陽離子型界面活性劑所製備之囊泡狀中孔洞氧化矽。為探討各種實驗變因對氧化矽型態的影響，本實驗將針對諸如界面活性劑間比例、反應的pH值、界面活性劑濃度、TEOS含量、反應溫度等不同變因一一討論，找出產率最佳的合成條件並整合其結果推測出合成機制。
本研究在適當反應條件下混合各成份，利用簡單的攪拌即可合成出結構完整、粒徑均勻、分散性佳的囊泡狀中孔洞氧化矽，此合成方法簡便且再現性高，因此對於自然界生物成礦的形成機制及理論，具有很高的參考價值。

In nature many complex biological structures such as skeleton, teeth of organisms and diatoms, shells in the sea are composed of highly joint complexes of organic and inorganic compounds. Applying the concept to synthesizing various forms of nano-materials, this research uses organic compound-based template which enables the condensation of inorganic compounds through molecular self-assembly process and forming of organic-inorganic nano-composite materials, hoping that morphologies similar to natural diatoms could be synthesized and in this way offers a new insight of bionics material.
In order to acquire organic-inorganic complex material, this experiment utilize surfactant as organic template and combined it with inorganic species (Sodium silicate solution, Tetraethyl orthosilicate).In a mixture of cationic and anionic surfactants (i.e. catanionic surfactant), various micelle structures, including cylindrical micelle, vesicles micelle, as well as laminar structure can not only be obtained by adjusting the molar ratio between the two composites but also used as a template of silica mesostructure which has spectacular morphologies. Mixtures of anionic and cationic surfactants through the electrostatic association of their oppositely charged polar head groups consist of vesicles which are able to mimic the structure of phospholipids (double-chained amphiphiles)and thus be viewed as model systems for fluid interfaces and biomembranes. This research use proportioned mixture(SDS / Cn TMAB molar ratio,S ) of cationic surfactant (CnTMAX, n=12-18, X=Br or Cl) and anionic surfactant (SDS) as the organic template.Inorganic TEOS is then mixed with the template above for preparing vesicle-like mesoporous silica in the condition of pH3, 40℃)
This experiment can be divided into two main parts:
1. the vesicle-like mesoporous silica prepared from C14TMAB cationic surfactant.
2. alteration of carbonic chain length of cationic surfactant, using CnTMAB (n=12,16,18) to synthesize vesicle-like mesoporous silica.
This experiment focuses on variables including molar ratio and concentrations of different surfactants, pH values and temperatures of the reactions to discover the most productive reaction condition, following by integrating the results and speculating about probable mechanisms.
This research mix contents in proper circumstances and synthesize vesicle-like mesoporous silica which have intact structures, even diameters and high dispersibility by means of uncomplicated stirring. This method is simple and has high reproducibility and therefore has high reference values in developing mechanisms and theories of biomineralization.

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