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研究生: 陳思樺
Chen, Sih-Hua
論文名稱: 極低出生體重早產兒六個月伸手表現與一歲認知表現之相關性
Investigating the Relation between Goal-Directed Reaching at 6 Months and Cognitive Performance at 12 Months in Preterm Infants with Very Low Birth Weight
指導教授: 蔡佩倫
Tsai, Pei-Luen
學位類別: 碩士
Master
系所名稱: 醫學院 - 職能治療學系
Department of Occupational Therapy
論文出版年: 2014
畢業學年度: 102
語文別: 中文
論文頁數: 129
中文關鍵詞: 認知功能早產兒伸手表現極低出生體重
外文關鍵詞: cognition, preterm, reaching performance, very low birth weight
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  • 伸手表現為嬰兒第一個有意向的探索動作,與認知發展相關聯。極低體重早產兒(very low birth weight,VLBW,出生體重小於1500公克)隨著醫療技術進步存活率逐漸上升,然而即使無明顯腦傷,這些孩童至學齡期仍可能有認知功能問題。因此在嬰兒期是否有一早期指標可做為日後認知能力參考。極低體重早產兒伸手表現均較足月組差,但目前則缺乏極低體重嬰兒伸手表現與幼兒期認知表現相關的研究,早產兒相關的研究也不一致。因此本研究目的為探討極低體重早產兒6個月伸手表現與足月受試嬰兒之差異,探討極低體重早產兒6個月的伸手表現與12個月時的認知功能之相關性,及本研究自行發展之嬰兒伸手測驗對於極低體重早產兒認知遲緩之區辨效度。研究樣本將由「財團法人台灣早產兒基金會」南區極低體重早產兒長期追蹤計畫中招募45位嬰兒,足月組為足月出生且發展正常之嬰兒20名。以自行發展之『嬰兒伸手動作測驗』評估極低體重個案6個月時之伸手表現,並以其12個月發展追蹤之『貝萊嬰幼兒發展量表第三版』之認知分數,進行相關性探討。研究結果顯示極低體重早產兒在伸手探索表現顯著較長且缺乏,其出生時後腦室出血程度可能為影響因子,且此表現與其一歲時認知語言分數相關,但嬰兒伸手測驗之區辨效度則較為低落。因此,未來臨床上可以早期探索行做為之後認知、語言發展之參考,然而在發展遲緩的診斷上仍需使用標準化評估工具做進一步的評估。

    Reaching is the first intended actions of infants and correlates with cognition development. As technology and major advances in medical management, the survival rate and population ratio in infants born with VLBW have increased over recent years. Studies showed that even though the VLBW without major brain lesion, they are still possible to have subtle cognition problems at school age. In addition, infants born with VLBW have poor reaching performance than infants born full-term. The aim of the study was to investigate the differences in reaching performance between VLBW and full-term infants at 6 months and the correlation between reaching performance and cognition development. Last, to exam the discriminant validity of the Infant Reaching Test. We recruited 45 VLBW and 20 full-term infants. The Infant Reaching Test was used to assess infant’s reaching performance. The cognition at 12 months was evaluated by Bayley Scales for Infant Development Third Edition. Significant differences were found in reaching performance, especially in the time before hand activated. VLBW infants significantly need more time to executive their reaching performance. One risk factor of reaching was intraventricular hemorrhage. And their reaching performance was correlated with their scores of cognition and language performance at first year. But the discriminant validity of the Infant Reaching Test was low. The findings of this study provide evidence that VLBW infant’s reaching performance could be used as an index of their cognition and language ability in the future. But, the utility of The Infant Reaching Test still need to be further evaluated.

    中文摘要 I 英文摘要 II 誌謝 VII 目次 IX 表目錄 XII 圖目錄 XIII 第一章、緒論 1 第一節、研究動機與重要性 1 第二節、研究目的 3 第二章、文獻回顧 4 第一節、極低出生體重早產兒 4 壹、定義與簡介 4 貳、早期療育 6 參、嬰幼兒發展評估測驗 7 第二節、伸手重要性 13 壹、嬰兒探索行為 13 貳、嬰幼兒伸手發展 16 參、早產受試嬰兒伸手發展及與認知關聯 20 肆、伸手測驗之臨床觀察項目 24 第三節、總結與研究假設 26 第三章、研究方法 28 第一節、研究參與者 28 第二節、研究工具與測驗 29 壹、基本資料表 29 貳、嬰兒伸手測驗 29 參、皮巴迪動作發展量表 30 肆、嬰兒氣質評估問卷 31 伍、貝萊嬰幼兒發展測驗 31 陸、早產組出生狀況及危險因子 32 第三節、研究程序 33 第四節、資料收集與分析 34 壹、資料收集 34 貳、資料分析 37 第四章、結果 41 第一節、基本人口學資料 41 壹、人口學資料分析 41 第二節、嬰兒伸手動作測驗表現結果的差異 43 壹、極低出生體重早產組與足月組在嬰兒伸手動作測驗表現的差異 43 貳、高風險及低風險早產組與足月組在嬰兒伸手動作測驗表現的差異 44 第三節、極低體重早產組嬰兒伸手動作測驗表現之相關因子 46 壹、早產組嬰兒伸手動作測驗與各因子相關性 46 第四節、極低體重早產組嬰兒伸手動作測驗與認知表現相關 48 第五節、嬰兒伸手測驗之信效度 49 壹、嬰兒伸手測驗之常模建立 49 貳、嬰兒伸手測驗之施測者間信度 50 參、嬰兒伸手測驗之同時效度 50 肆、嬰兒伸手測驗之區辨效度 50 第五章、討 論 52 第一節、早產組與足月組受試嬰兒伸手動作測驗表現之差異 52 壹、嬰兒伸手測驗變項 52 貳、過往家庭環境經驗 57 第二節、極低體重早產組嬰兒伸手動作測驗表現之相關因子 58 壹、出生狀況 58 貳、環境 60 參、氣質 60 肆、過往家庭環境經驗 61 第三節、極低體重早產組嬰兒伸手動作測驗與認知表現相關性 62 壹、認知與伸手測驗變項 62 貳、接收性語言與伸手測驗變項 63 參、表達性語言與伸手測驗變項 64 第四節、嬰兒伸手測驗之信效度 66 壹、常模建立 66 貳、嬰兒伸手測驗之施測者間信度 66 參、嬰兒伸手測驗之同時效度 67 肆、嬰兒伸手測驗之區辨效度 67 第五節、研究限制及建議 69 第六章、結論及臨床意義 70 參考文獻 71

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