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研究生: 高安平
Kao, An-Ping
論文名稱: 南嶺前胡葉部與廣東山葡萄之成分研究
The constituents of the leaves of Peucedanum longshengense and whole plant of Ampelopsis cantoniensis
指導教授: 吳天賞
Wu, Tian-Shung
學位類別: 碩士
Master
系所名稱: 理學院 - 化學系
Department of Chemistry
論文出版年: 2006
畢業學年度: 94
語文別: 中文
論文頁數: 156
中文關鍵詞: 南嶺前胡廣東山葡萄
外文關鍵詞: peucedanum longshengense, ampelopsis cantoniensis
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  • 由南嶺前胡(Peucedanum longshengense)之葉部分離得到39個化合物,其中38個分別為:scopoletin (1)、 (R)-peucedanol (2)、 bergapten (31)、 isoimperatorin (32)、 (-)-(R)-oxypeucedanin (33)、 (+)-oxypeucedanin hydrate (34)、 (-)-pangelin (39)、 (+)-marmesin (72)、 deltoin (77)、 3'-(S)-4'-(S)-khellactone (132)、qainhucoumarin C (134)、 3'-(S)-4'-(S)-4'-tigloylkhellactone (136)、 laserpitin (135)、 qainhucoumarin D (139)、 pteryxin (142)、 3'-(S)-O-acetyl-4'-(R)-O- tigloylkhellactone (161)、 isoquercitrin (186)、 -sitosterol(228)、 stigmasterol (229)、 -sitosteryl-3-O--glucopyranoside (230)、 9-hydroxy-4-(3-methylbut-2- enyloxy)furo[3,2-g]chromen-7-one (253)、 isooxypeucedanin (254)、 3'-(S)-O- tigloyl-4'-(S)-O-acetylkhellactone (255)、 (-)-isosamidin (256)、 3'-(R)-acetoxy-4'-(S)- hydroxy-3',4'-dihydroseselin (257)、 peucedanoside-A (258)、 peucedanoside-B (259)、 (+)-8-hydroxy-p-menth-6-en-7-al (260)、 3-hydroxy-4- isopropylcyclohexenecarbaldehyde (261)、 (+)-syringareainol (262)、 perlolyrin (263)、 lycoperodine-1 (264)、 3,4-dimethoxyacetophenone (265)、 2-acetyl-5- hydroxymethylphenol (266)、 2-oxyl-4-methyl-acetophenon (267)、4-hydroxycinnamic acid (268)、 N-tetracosanoyltyramine (269)、 erythritol (270)。其中peucedanoside-A (258)、 peucedanoside-B (259) 和(+)-8-hydroxy-p-menth-6- en-7-al (260)為首次報導之新化合物。
    研究發現由南嶺前胡葉部分離得到的成分與大陸學者P. Huang對本植物之根部所做的研究相似,皆含大量的khellactone type骨架衍生物。由所分離得到的khellactone type骨架化合物與過去報導的此類化合物歸納出判別khellactone type 骨架上C-3'與C-4'相對立體位向的快速簡易方法。
    另外著手研究廣東山葡萄(Ampelopsis cantoniensis)之化學成分,並分離得到21個化合物,其中18個分別為:scopoletin (1)、 scoparone (3)、 syringic acid (318)、 3,4,5-trimethoxy-benzenemethanol (319)、 pinoresinol (320)、 -sitosterol (228)、 - sitosteryl----D-glucoside (230)、 stigmast-4-en-3-on (321)、stigmasta-4,22-dien-3-on (322)、 6-hydroxystigmast-4-en-3-one (323)、6-hydroxystigmast-4-en-3-one (324)、 betulinic acid (325)、 ursolic acid (326)、132(S)-methoxypheophorbide-a (327)、 methyl 21-hydroxy-21(S)-pheophorbide-a (328)、 132(S)-methoxypheophorbide-a methyl ester (329)、 methyl-21-hydroxy- 21(S)-pheophorbide-a (330)、 methyl-21-hydroxy-21(R)-pheophorbide-b(331)。
    研究發現由廣東山葡萄分離得到的成分以sterols 和chlorophylls 含量最多,與它種植物差異性較大。
    以上新化合物的結構乃利用NMR 1D與2D光譜的分析加以決定,而已知的化合物則是與文獻所報導的物理與化學光譜數據進行比對得到確認。

    Detailed chemical examination of the MeOH extract of the leaves of Peucedanum longshengense has led to the isolation of thirty-nine compounds. Among them, thirty-eight compounds were identified by spectroscopic analyses as scopoletin (1), (R)-peucedanol (2), bergapten (31), isoimperatorin (32), (-)-(R)-oxypeucedanin (33), (+)-oxypeucedanin hydrate (34), (-)-pangelin (39), (+)-marmesin (72), deltoin (77), 3'-(S)-4'-(S)-khellactone (132), qainhucoumarin C (134), 3'-(S)-4'-(S)-4'- tigloylkhellactone (136), laserpitin (135), qainhucoumarin D (139) , pteryxin (142), 3'-(S)-O-acetyl-4'-(R)-O-tigloylkhellactone (161), isoquercitrin (186), -sitosterol (228), stigmasterol (229), -sitosteryl-3-O--glucopyranoside (230), 9-hydroxy- 4-(3-methylbut-2-enyloxy)furo[3,2-g]chromen-7-one (253), isooxypeucedanin (254), 3'-(S)-O-tigloyl-4'-(S)-O-acetylkhellactone (255), (-)-isosamidin (256), 3'- (R)-acetoxy-4'-(S)-hydroxy-3',4'-dihydroseselin (257), peucedanoside-A (258), peucedanoside-B (259), (+)-8-hydroxy-p-menth-6-en-7-al (260), 3-hydroxy- 4-isopropylcyclohexenecarbaldehyde (261), (+)-syringaresinol (262), perlolyrin (263), lycoperodine-1 (264), 3, 4-dimethoxyacetophenone (265), 2-acetyl- 5-hydroxymethylphenol (266), 2-hydroxy-4-methylacetophenone (267), 4-hydroxycinnamic acid (268), N-tetracosanoyltyramine (269),and erythritol (270).
    Compounds, peucedanosides-A (258), peucedanosides-B (259), and (+)-8- hydroxy-p-menth-6-en-7-al (260), were new compounds.Roots of P. longshengense were reported as rich source of khellactone type coumarins. As expected, the leaves of titled plant has also yielded several khellactone derivatives. It is worthy to mention that with the experience of spectral analysis of several kallactone derivatives, I found an easy method to distinguish the cis and trans forms of substituents at C-3' and C-4'.
    In addition, a thorough investigation of the MeOH extract of whole plant of Ampelopsis cantoniensis for its chemical constituents resulted in the isolation of twenty-one compounds. Of which, eighteen compounds were identified by detailed spectral analyses as scopoletin (1), scoparone (3), syringic acid (318)、3,4,5-trimethoxybenzylalcohol (319), pinoresinol (320), -sitosterol (228)、-sitosteryl----D-glucoside (230), stigmast-4-en-3-one (321), stigmasta- 4,22-dien-3-one (322), 6-hydroxystigmast-4-en-3-one (323), 6- hydroxystigmast-4-en-3-one (324), betulinic acid (325), ursolic acid (326), 132(S)-methoxypheophorbide-a (327), methyl 21-hydroxy-21(S)-pheophorbide-
    a (328), 132(S)-methoxypheophorbide-a methyl ester (329), methyl-21- hydroxy-21(S)-pheophorbide-a (330), and methyl-21-hydroxy-21(R)-pheophorbide- b(331).These results indicated that A. cantoniensis contained lot of sterols and chlorophylls.

    英文摘要 I 中文摘要 II 第一章 緒論 1 第一節 研究動機 1 第二節 植物型態 1 第三節 植物分布 1 第二章 前胡屬(Peucedanum)之藥理研究回顧 3 第三章 前胡屬植物之成分研究回顧 6 第四章 南嶺前胡(Peucedanum longshengense)葉部之萃取與分離 36 第五章 南嶺前胡成分之構造研究 44 第一節 Khellactone type骨架化合物的簡介 44 第二節 (-)-cis-Khellactone (132) 之構造研究 47 第三節 Laserpitin (135) 之構造研究 50 第四節 Qainhucoumarin D (139) 之構造研究 55 第五節 3'-(S)-O-Acetyl-4'-(R)-O-tigloylkhellactone (161) 之構造研究 59 第六節 Pteryxin (142) 之構造研究 64 第七節 3'-(S)-O-Tigloyl-4'-(S)-O-acetylkhellactone (255) 之構造研究 69 第九節 (-)-(R)-Peucedanol (2) 之構造研究 77 第十節 Peucedanoside-A (258) 之構造研究 81 第十一節 Peucedanoside-B (259) 之構造研究 86 第十二節 Isoquercitrin (186) 之構造研究 91 第十三節 2-Acetyl-5-hydroxymethylphenol (266) 之構造研究 95 第十四節 Lycoperodine-1 (264) 之構造研究 97 第十五節 (+)-8-Hydroxy-p-menth-6-en-7-al (260) 之構造研究 100 第十六節 其他化合物的構造研究 104 第六章 廣東山葡萄( Ampelopsis cantoniensis )之成分研究 105 第一節 研究動機 105 第二節 植物形態 105 第三節 山葡萄屬之藥理回顧 106 第四節 成分回顧 106 第五節 廣東山葡萄(Ampelopsis cantoniensis)之萃取與分離 115 第七章 結論 121 第八章 實驗部分 125 第一節 本實驗所使用之儀器與藥品 125 第二節 植物的萃取與分離 126 第三節 光譜數據 131 參考文獻 143

    1.顏焜熒,常用之中藥之藥理,國立中國醫藥研究所,台北, Vol. II, p.54-59,1970。
    2.Shan, R. H.; Shen, M. L.; Wang, T. S.; Pu, F. T.; Shen, K. M.; Chang, H. T. “New taxa of the Chinese Umbelliferae”, Acta Phytotaxonomica Sinica, 26,
    p.304-311, 1986。
    3.Huang, P.; Zheng, X. Z.; Nishi, M.; Nakanishi, T. “Isolation and structure
    elucidation of longshengensin A from Peucedanum longshengense.”, Yaoxue
    Xuebao, 32, p.62-64, 1997。
    4.Shan, R. H.; Shen, M. L.; Wang, T. S.; Pu, F. T.; Shen, K. M.; Chang, H. T. “New taxa of the Chinese Umbelliferae”, Acta Phytotaxonomica Sinica, 24,
    p.306-307, 1986.
    5.Lu, M.; Nicoletti, M.; Battinelli, L.; Mazzanti, G. “Isolation of
    praeruptorins A and B from Peucedanum praeruptorum Dunn. and their general
    pharmacological evaluation in comparison with extracts of the drug”,
    Farmaco, 56, p.417-420, 2001.
    6.Rani, P.; Khullar, N. “Antimicrobial evaluation of some medicinal plants for
    their anti-enteric potential against multi-drug resistant Salmonella typhi”,
    Phytother. Res., 18, p.670-673, 2004.
    7.Hisamoto, M.; Kikuzaki, H.; Nakatani, N. “Constituents of the leaves of
    Peucedanum japonicum Thunb. and their biological activity”, J. Agric. Food
    Chem., 52, p.445-450, 2004.
    8.Vellutini, M.; Baldovini, N.; De, R.; Dominique, S.; Tomi, F.; Casanova, J.
    “Cycloavandulyl and isocycloavandulyl esters from Peucedanum paniculatum L.,
    an endemic species to Corsica”, Phytochemistry, 66, p.1956-1962, 2005.
    9.Schinkovitz, A.; Gibbons, S.; Stavri, M.; Cocksedge, M.; Bucar, F.,
    “Ostruthin: an antimycobacterial coumarin from the roots of Peucedanum
    ostruthium”, Planta Med., 69, p.369-371, 2003.
    10.Okuyama, T.; Takata, M.; Nishino, H.; Nishino, A.; Takayasu, J.; Iwashima,
    A., “Studies on the antitumor-promoting activity of naturally occurring
    substances. II. Inhibition of tumor-promoter-enhanced phospholipid
    metabolism by umbelli- ferous materials”, Chem. Pharm. Bull., 38, p.1084-
    1086, 1990.
    11.Wu, J. Y.; Fong, W. F.; Zhang, J. X.; Leung, C. H.; Kwong, H. L.; Yang, M.
    S.; Li, D.; Cheung, H. Y. “Reversal of multidrug resistance in cancer cells
    by pyranocoumarins isolated from Radix Peucedani”, Eur. J. Pharmacol., 18,
    p.9-17, 2003.
    12.Zhang, J. X.; Fong, W. F.; Wu, J. Y.; Yang, M.; Cheung, H. Y.
    “Pyranocoumarins isolated from Peucedanum praeruptorum as differentiation
    inducers in human leukemic HL-60 cells”, Planta Med., 69, p.223-229, 2003.
    13.Morioka,T.; Suzui, M.; Nabandith, V.; Inamine, M.; Aniya, Y.; Nakayama, T.;
    Ichiba, T.; Mori, H.; Yoshimi, N. “The modifying effect of Peucedanum
    japonicum, a herb in the Ryukyu Islands, on azoxymethane-induced colon
    preneoplastic lesions in male F344 rats”, Cancer Lett., 2, p.133-141, 2004.
    14.Schillaci, D.; Venturella, F.; Venuti, F.; Plescia, F. “Antimicrobial and
    antiproliferative activity of Peucedanum nebrodense Strohl”, J.
    Ethnopharmacol., 87, p.99-101, 2003.
    15.Aida, Y.; Kasama, T.; Takeuchi, N.; Tobinaga, S. “The antagonistic effects
    of khellactones on platelet-activating factor, histamine, and leukotriene
    D4”, Chem. Pharm. Bull., 43, p.859-867, 1995.
    16.Chen, I. S.; Chang, C. T.; Sheen, W. S.; Teng, C. M.; Tsai, I. L.; Duh, C.
    Y.; Ko, F. N. “Coumarins and antiplatelet aggregation constituents from
    Formosan Peucedanum japonicum”, Phytochemistry, 41, p.525-530, 1996.
    17.Hsiao, G.; Ko, F. N.; Jong, T. T.; Teng, C. M. “Antiplatelet action of 3',
    4'-diisovalerylkhellactone diester purified from Peucedanum japonicum
    Thunb”, Biol. Pharm. Bull., 21, p.688-692, 1998.
    18.Ji, Y.; Rao, M. “Effects of Peucedanum praeruptorum extract on blood
    pressure, left ventricular hypertrophy and hemodynamic changes in left
    ventricular hypertrophied hypertensive rats”, Zhongcaoyao, 27, p.413-416,
    1996.
    19.Rao, M.; Liu, W.; Liu, P. “Effects of praeruptorin C on vascular
    hypertrophy, [Ca2+], collagen content and NO in renovascular and
    spontaneously hypertensive rats” .Yaoxue Xuebao, 36, p.165-169, 2001.
    20.Aida, Y.; Kasama, T.; Takeuchi, N.; Chiba, M.; Tobinaga, S.,
    “Pharmacological activities of khellactones, compounds isolated from
    Peucedanum japonicum Thunb. and Peucedanum praeruptorium Dunn.”, Methods
    Find. Exp. Clin. Pharmacol., 20, p.343-351, 1998.
    21.Lee, S. O.; Choi, S. Z.; Lee, J. H.; Chung, S. H.; Park, S. H.; Kang, H. C.;
    Yang, E. Y.; Cho, H. J.; Lee, K. R. “Antidiabetic Coumarin and Cyclitol
    Compounds from Peucedanum japonicum”, Archives of Pharmacal Research, 27,
    p.1207-1210, 2004.
    22.Hisamoto, M.; Kikuzaki, H.; Ohigashi, H.; Nakatani, N. “Antioxidant
    compounds from the leaves of Peucedanum japonicum Thunb.”, J. Agric. Food.
    Chem., 51, p.5255-5261, 2003.
    23.Zhang, C.; Li, W.; Xiao, Y. Q. “Comparative studies on pharmacological
    effects of the main chemical constituents of Peucedanum praeruptorum from
    He'nan and Jiangxi”, Zhongguo Zhong Yao Za Zhi., 30, p.1356-1358, 2005.
    24.Dadak, V. “Isolation of several substances from the the roots of Peucedanum
    alsaticum”, Monatsh. Chem., 88, p.1116-1118, 1957. [C.A.1958, 52, p.9513.]
    25.Hadacek, F.; Greger, H.; Grenz, M.; Bohlmann, F. “Olefinic and acetylenic
    butenolides from Peucedanum alsaticum I.”, Phytochemistry, 26, p.1527-1529,
    1987.
    26.Kuznetsova, G. A.; Markelova, E. V.; Mark, E. P.; Eugen, K.; Stamenko, P.
    “(-)-3'-(R)-hydroxy-4'-(S)-methoxy-3',4'-dihydroxanthyletin from the roots
    of the Peucedanum arenarium”, Phytochemistry, 17, p.1805-1806, 1978.
    27.Zheleva, A.; Bubeva-Ivanova, L.; Spasov, S. L. “Natural coumarins. III.
    Structure of peuarenarin, a new coumarin from Peucedanum arenarium” Z.
    Naturforsch. B, 26, p.113-114, 1971.
    28.Slobodan, M.; Dragoslav, J.; Marina, N.; Gorica, R.; Predrag, Z.; Marina, N,
    Violeta, R.; Vlatak, V. “Furo- and pyranocoumarins from plant species
    Angelica silvestris and Peucedanum austriacum” J. Serb. Chem. Soc., 58,
    p.997-1001, 1993 [C.A. 1994, 121, 276692b.]
    29.Milutin, S.; Slobodan, M.; Miodrag, D.; Slavisa, M.; Ilija, K.; Ljiljana, K.
    “Stereoisometric pyranocoumarins (khellactone esters), pyrano- and
    furanochromones from Peucedanum austriacum (Jacq.)”, Glas. Hem. Drus.
    Beograd, 49, p.5-15, 1984. [C.A. 1984, 101, 107325r.]
    30.Hadacek, F.; Mueller, C.; Werner, A.; Greger, H.; Proksch, P., “Analysis,
    isolation and insecticidal activity of linear furanocoumarins and other
    coumarin derivatives from Peucedanum (Apiaceae: Apioideae)”, J. Chem.
    Ecol., 20, p.2035-2054, 1994.
    31.Kozowska, V.; Zheleva, A.; Pangarova, T. “7-(β-D-glucopyranosyloxy)-5-
    hydroxy-2-methylchromone from peucedanum austriacum”, Int. Conf. Chem.
    Biotechnol. Biol. Act. Nat. Prod., 3, p.114-116, 1981. [C.A. 1982, 97,
    88678p.]
    32.Campbell, W. E.; Mathee, S.; Wewers, F. “Phytochemical studies on the
    blister bush, Peucedanum galbanum”, Planta Med., 60, p.586-587, 1994.
    33.Ferdinand, B.; Michael, G.; Christa, Z. “Nautrally occurring coumarin
    dervatives. XII. New coumarins from Peucedanum and Pteronia species”, Chem.
    Ber., 108, p.1955-1958, 1975.
    34.Agarwal, S. G.; Vashist, V. N.; Atal, C. K. “Coumarins from Peucedanum
    dhana seeds”, Indian J. Chem., 13, p.1108, 1975. [C.A. 1976, 84, 40752n].
    35.Avramenko, L. G.; Sklyar, Y. E.; Pimenov, M. G. “Coumarins of Peucedanum
    baicalense”, Khim. Prir. Soedin., 11, p.421-422, 1975. [C.A. 1976, 84,
    28003m].
    36.Prokopenko, A. “Coumarins in some Umbelliferae species”, Dosw. Wygloszone
    Symp., p.90-99, 1970. [C.A. 1973, 78, 69216c].
    37.Baranauskaite, D.; Nikonov, G. K. “Chemical study of Peucedanum tauricum
    and Peucedanum calcareum”, Aptechnoe. Delo., 14, p.25-28, 1965. [C.A. 1965,
    62, 76085].
    38.Rene, S. “Essential oil and saturated hydrocarbon from Peucedanum
    cervaria”, Compt. Rend., 242, p.2853-2854, 1956.
    39.Desai, H. K.; Cisowski, “Chemical investigation of some Indian plants”,
    Rocz. Chem., 49, 1823-1828, 1975.
    40.Rao, G. X.; Sun, H. D.; Lin, Z. W.; Nie, F. “Chemical constituents of the
    traditional Chinese medicine Qain-Hu”, Taiwan Chanwu Yanjiu Yu Kaifa, 5,
    p.1-17. 1993. [C.A. 1994, 121, 53896].
    41.Asahara, T.; Sakakibara, I.; Okuyama, T.; Shibata, S. “Studies on coumarins
    of a Chinese drug “Qain-Hu”, V. Coumarin-glycosides from “Zi Hua Qain
    Hu”, Planta Med., 50, p.488-492, 1984.
    42.Nikonov, G. K.; Pimenov, M. G. “Coumarins of Peucedanum deltoideum”, Rast.
    Resurl., 3, p.248-250. 1967. [C.A.1967, 968, 909g].
    43.Arima, J. “The constituention of nodakenin, a new glucoside from Peucedanum
    decursivum Maxim”, I. Bull. Chem. Soc. Japan, 4, p.113-119, 1929.
    44.Spaeth, E.; Kainrath, P. “Natural coumains. XX. Constituents of the
    nodakenin from Peucedanum decursivum Maxim”, Chem. Ber., 69, p.2062-2065,
    1936. [C.A.1936, 23, 4708]
    45.Arima, “Content of oils and their localization in the tissues of Peucedanum
    cervaria”, Chem. Zentralbl., 100, p.1698, 1929.
    46.Kong, L.; Yao, N. H.; Masatake, N. “Two new xanthyletin-type coumarins from
    Peucedanum decursivum”, Heterocycles, 53, p.2019-2025, 2000.
    47.Yao, N.; Kong, L. “Chemical constituents of Peucedanum decursivum”, Yaoxue
    Xuebao, 36, p.351-355, 2001.
    48.Hata, K.; Kozawa, M.; Yen, K. Y. “The constitution of peuformosin, a new
    coumarin isolated from the root of Peucedanum formosanum Hayata
    (Umbelliferae)”, Chem. Pharm. Bull., 14, p.442-446. 1966.
    49.Malaviya; Dutt, “Flavonoid compounds in herbs of Peucedanum oreoselinum”,
    Proc.-Indian Acad. Sci. Sect.,12, p251-257. 1940.
    50.Nelson, E. K. “The volatile oil and resin of Cynomarathrum nuttallii”, J.
    Am. Chem. Soc., 55, p.3400, 1933.
    51.Siddiqui, S. A.; Sen, A. B. “Coumarins of Peucedanum grande seed”,
    Lloydia, 35, p.84-86, 1972. [C.A. 1972, 77, 85639c].
    52.Thakkar, S. M.; Deshmukh, V. K.; Saoji, A. N.; Parashar, V. V. “Chemical
    examination of fruits and leaves of Peucedanum grande”, J. Indian Chem.
    Soc., 64, p.646-647, 1987.
    53.Gonzalez, A. G.; Barroso, J. T.; Cardona, R. J.; Medina, J. M.; Rodriguez,
    L. F. “Umbelliferae components. XVI. Coumarins from Peucedanum
    hispanicum”, An. Quim., 73, p.1188-1191. 1977. [C.A. 1978, 89, 193816q].
    54.Shagova, L. I.; Kuznetsova, G. A.; Markova, L. P.; Vinogradova, V. M.
    “Furocoumarins from peucedanum hystrix roots”, Khim. Prir. Soedin., 18,
    p.518. 1981. [C.A. 1982, 96, 31627w].
    55.Chi, H. J.; Kim, H. S. “Coumarins from the roots of Peucedanum insolens
    Kitagawa”, Soul Taehakkyo Saengyak Yonguso Opjukjip, 20, p.46-48. 1981.
    [C.A. 1983, 98, 59799u].
    56.Yasuji, Y.; Hsu, C. S.; Kazuo, I.; Michio, S.; Hsu, H. Y.; Chen, Y. P. “Two
    new khellactone esters from Peucedanum japonicum thunb”, Tetrahedron Lett.,
    15, p.2513-2516, 1974.
    57.Yasumasa, I.; Izumi, M.; Yutaka, T. “Dihydropyranocoumarins from
    Peucedanum japonicum”, Phytochemistry, 33, p.1543-1545, 1993.
    58.Nobuharu, S.; Isao, K.; Nobusuke, K. "On the isolation of (+)-samidin from
    the roots of Peucedanum japonicum.", Phyochemistry, 31, p.4303-4306, 1992.
    59.Duh, C. Y.; Wang, S. K.; Wu, Y. C. “Cytotoxic pyranocoumarins from the
    aerial parts of Peucedanum japonicum”, Phytochemistry, 30, 8, p.2812-2814,
    1991.
    60.Nikonov, G. K.; Perel'son, M. E.; Pimenov, M. G. “Chemical studies of
    Peucedanum littorale”, Khim. Prirodn. Soedin. Akad. SSR., 2, p.285-287,
    1996. [C.A. 1967, 66, 485j].
    61.Eugen, K.; Slavka, P.; Milica, B.; Sanda, D. “Coumarins from roots and
    fruits of Peucedanum longifolium”, Arh. Farm., 38, p.135-138, 1988. [C.A.
    1989, 10, 132220w].
    62.Ferdinand, B.; Michael, G. “Naturally occurring terpene deivatives. LIV.
    New terpene aldehyde esters from Peucedanum luxurians Tammamsch”, Chem.
    Ber., 109, p.788-790, 1976.
    63.Roa, G.; Song, H.; Wang, X.; Liu, Q.; Sun, H. “Coumarins of Peucedanum
    macilentum French” Tianran Chanwu Yanjiu Yu Kaifa, 9, p.34-36, 1997. [C.A.
    1999, 129820z].
    64.Huang, P.; Lu, C.; Lai, M.; Zheng, X. “Chemical constituents of mashaqianhu
    Peucedanum mashanense”, Zhongcaoyao, 26, p.511-513, 1995.
    65.Liu, B.; Lai, M.; Cai, Q.; Peng, W.; Zheng, X. “Separation and
    determination of chemical constituents of essential oil of Peucedanum
    mashanense Shan et Sheh”, Fenxi Huaxue, 23, p.885-888, 1995.
    66.Hung, P.; Zheng, X. Lai, M.; Rao, W.; Xi, Z.; Zhong, X. “Studies on
    chemical constituents of Peucedanum medicum Dunn. var. gracil Dunn. Ex Shan
    et Sheh”, Zhongguo Zhongyao Zazhi, 25, p.222-224, 2000.
    67.Nikonov, G. K. “Structure of mogoltin, a coumarin from Peucedanum
    mogoltavicum roots”, Khim. Prir. Soedin., 7, p.572-576, 1971.
    68.Khasanov, T. K.; Malikov, V. M.; Melibadv, S. “Structure and configuration
    of tavimolidin”, Khim. Prir. Soedin., 15, p.480-483, 1979.
    69.Nikonov, G. K.; Ivashenko, A. A. “Peucedanum morisonii”, Zh.Obshch. Khim.,
    33, p.2740-2744, 1963. [C.A. 1964, 60, 7878f].
    70.Zaretskii, V. I.; Vul'fson, N. S.; Chetverikova, L. S.; Zaretskii, V. G. “A
    mass spectrometric study of heterocyclic compounds. The structure of
    peumorisin, a new natural hydroxycoumarin extracted from Peucedanum
    morisonii”, Zh. Obshch. Khim., 34, p.3655-3659, 1964.[C.A. 1965, 62, 9097a].
    71.Valutskaya, A. G. “Flavonoids of Peucedanum morisonii”, Khim. Prir.
    Soedin., 10, p.671, 1974. [C.A. 1975, 82, 83019e].
    72.Antonio, G.; Cardona, R. J.; Medina, J. M.; Luis, F. R. “Components of
    Umbelliferae. VI. Coumarins of Peucedanum officinale L”, An. Quim., 72,
    p.60-64, 1976. [C.A. 1977, 86, 60453k].
    73.Prokopenko, A. P. “Isolation and determination of athamantin”, Farmatsevt.
    Zh., 20, p.47-50, 1965. [C.A. 1966, 64,3947b].
    74.Lemmich, E.; Lemmich, J.; Nielsen, B. E. “Constituents of umbelliferous
    pants. XIV. Coumarins of Peucedanum oreoselinum”, Acta Chem. Scand., 24,
    p.2893-2900, 1970.
    75.Prokopenko, A. P. “Peucenidine, a new furocoumarin isolated from the fruit
    of Peucedanum oreoselinum”, Zh. Obshch. Khim., 34, p.4111-4116, 1964. [C.A.
    1965, 62, 9117c].
    76.Bodalski, T.; Cisowaski, W. “Flavonoid compounds in herbs of Peucedanum
    oreoselinum”, Diss. Pharm. Pharmacol., 23, p.173-177, 1971. [C.A. 1971, 75,
    31221a].
    77.Lemmich, E. “Peucelinendiol, a new acyclic diterpenoid from Peucedanum
    oreoselinum”, Phytochemistry, 18, p.1195-1197, 1979.
    78.Sami, K. A.; Szendrel, K.; Novak, I.; Reisch, J. “Coumarin glycosides from
    Peucedanum ostruthium”, Phytochemistry, 14, p.1461-1462, 1975.
    79.Reisch, J.; Khaled, S. A.; Szendrei K.; Novák, I. “5-Alkoxyfuranocoumarins
    from Peucedanum ostruthium”, Phytochemistry, 14, p.1889-1890, 1975.
    80.Varga, E.; Szendrei, K.; Orcsik, I.; Hanuder, M.; Novak, I.; Reisch, J.
    “Study of the coumarins of Peucedanum ostruthium fruit. II”, Herba Hung.,
    17, p.91-97, 1978. [C.A. 1978, 89, 56439e].
    81.Hiermannc, A.; Schantlc, D.; Schubert-Zsilavecza, M.; Reinerb, J.
    “Coumarins from Peucedanum ostruthium”, Phytochemistry, 43, p.881-883, 1996.
    82.Varga, E.; Simokovics, J.; Szendrei, K.; Reisch, J. “Furanocoumarins and
    chromones from the fruits of Peucedanum ostruthium L. (Umbelliferae)”,
    Fitoterapia, 50, p.259-264, 1979. [C.A. 1980, 93, 41614s].
    83.Cisowski, W. “Flavonoid compounds in some species of Peucedanum genus”,
    Rocz. Chem., 49, p.1823-1830, 1975. [C.A. 1976, 84, 71477f].
    84.Wojciech, C. “New acylated glucoside of quercetin from Peucedanum
    ostruthium”, 48, p.1417, 1974. [C.A. 1975, 82, 82965y].
    85.Gijbels, M. J. M.; Fischer, F. C.; Scheffer, J. J. C.; Svendsen, A. B.
    “Phthalides in roots of Capnophyllum peregrinum and Peucedanum ostruthium”,
    Planta Med., 50, p.110-114, 1984.
    86.Vuorela, H.; Erdelmeier, C. A. J.; Nyiredy, S.; Dallenbach-Toelke, K.;
    Anklin, C.; Hiltunen, R.; Sticher, O. “Isobyakangelicin angelate; a novel
    furanocoumarin from Peucedanum palustre”, Planta Med., 54, p.538-42, 1988.
    87.Nielsen, B. E.; Lemmich, J. “Constituents of umbelliferous plants. VII.
    Coumarins from the fruits of Peucedanum palustre- structure of two new
    coumarins”, Acta. Chem. Scand., 19, p.1810-1814, 1965.
    88.Bagirov, V. Y.; Belyi, M. B. “Study of some representatives of the
    Umbelliferae family”, Khim. Prir. Soedin., 2, p.250-251, 1982. [C.A. 1982,
    97, 159497s].
    89.Kong, L.; Pei, Y.; Li, X.; Zhu, T. “Chemical constituents of the root of
    whiteflower hogfennel Peucedanum praeruptorum”, Zhongcaoyao, 24, p.401-404,
    1993.
    90.Kong, L. Y.; Pei, Y. H.; Li, X.; Wang, S. X.; Hou, B. L.; Zhu, T. R. “The
    isolation and identification of qianhucoumarin B and qianhucoumarin C from
    Peucedanum praeruptorum”, Yaoxue Xuebao, 28, p.772-776, 1993.
    91.Kong, L. Y.; Li, Y.; Min, Z. D.; Li, X.; Zhu, T. R. “Coumarins from
    Peucedanum praeruptorum”, Phytochemistry, 41, p.1423-1426, 1996.
    92.Kong, L. Y.; Li, X.; Pei, Y. H.; Yu, R. M.; Min, Z. D.; Zhu, T. R.
    “Isolation and structure elucidation of baihuaqianhuoside and Pd-C-I from
    Peucedanum praeruptorum”, Yaoxue Xuebao, 29, p.276-280, 1994.
    93.Takata, M.; Okuyama, T.; Shibata, S. “Studies on coumarins of a Chinese
    drug, Qian-Hu; VIII. Structures of new coumarin glycosides of Bai-Hua Qian-
    Hu” Planta Med., 54, p.323-327, 1988.
    94.Ye, J.; Zhang, H.; Yuan, C. “Isolation and identification of coumarin
    praeruptorin E from the root of the Chinese drug Peucedanum praeruptorum
    Dunn. (Umbelliferae)”, Yaoxue Xuebao, 17, p.431-434, 1982.
    95.Kong, L. Y.; Li, Y.; Niwa, M. “A new pyranocoumarin from Peucedanum
    praeruptorum”, Heterocycles, 60, p.1915-1919, 2003.
    96.Takata, M.; Shibata, S.; Okuyama, T. “Studies on coumarins of a Chinese
    drug Qian-Hu; Part X. Structures of angular pyranocoumarins of Bai-Hua Qian-
    Hu, the root of Peucedanum praeruptorum.", Planta Med., 56, p.307-311, 1990.
    97.Kong, L.; Pei, Y.; Li, X.; Zhu, T. “New compounds from Peucedanum
    praeruptorum”, Chin. Chem. Lett., 4, p.37-38, 1993. [C.A. 1994, 121,
    31073x].
    98.Liu, B.; Lai, M.; Peng, W.; Cai, Q.; Zheng, X. “Studies on chemical
    constituents of essential oil from Guangxi qianhu (Peucedanum
    quangxiense)”, Zhongcaoyao, 27, p.588-589, 1996.
    99.Rao, G. X.; Sun, H. D.; Lin, Z. W.; Hu, R. Y. “Chemical constituents of the
    traditional Chinese medicine Yunqianhu (Peucedanum rubricaule Shan et
    Sheh.)”, Yaoxue Xuebao, 26, p.30-36, 1991. [C.A. 1991, 115, 214616x].
    100.Soine, T. O.; Zheleva, A.; Mahandru, M. M.; Erhardt, P.; Bubeva-Ivanova, L.
    “Natural coumarins. VII. Isolation and structure of a new coumarin,
    peuruthenicin, from Peucedanum ruthenicum”, J. Pharm. Sci., 62, p.1879-
    1880, 1973.
    101.Kerimov, S. S. “Furocoumarins of Peucedanum ruthenicum”, Khim. Prir.
    Soedin., 16, p.92-93, 1979. [C.A. ,1979, 91, 52702d].
    102.Kozovska, V.; Zheliva, A. “Natural coumarins. X. A new furocoumarin, 8-
    methoxypeucedanin from the roots of Peucedanum ruthenicum”, Planta Med.,
    60-63, 1980.
    103.Lilia, B. I.; Zheleva, A.; Savchev, P. “Coumarin and flavonoid composition
    of Peucedanum ruthenicum”, Khim. Prir. Soedin., 5, p.594, 1969. [C.A.
    1970, 73, 73827s].
    104.Gonzalez, A.; Cardona, R. J.; Diaz, C. E.; Medina, J. M.; Rodriguez, L. F.
    “Umbelliferae components. XIX. Coumarins of Peucedanum stenocarpum Boiss
    and Revter and of Scandix pectens-veneris L”, An. Quim., 74, p.637-640,
    1978. [C.A. 1978, 89, 176305e].
    105.Ahluwalia, V. K.; Chandra, P. “Structure of stenocarpin and its
    isobutyrate”, Indian J. Chem., Sect. B, 15B, p.620-622, 1977. [C.A. ,
    1978, 88, 62261m].
    106.Bartnik, M.; Glowniak, K.; Mardarowicz, M. “Essential oil from fruit of
    Peucedanum tauricum Bieb”, Acta. Pol. Pharm., 59, p.457-459, 2002.
    107.Nakabayashi, T.; Kubo, I.; Yoshimoto, M. “Coumarin derivatives in Angelica
    ubatakensis, Peucedanum terebinthaceum, and Bulpleurum falcatum var.
    komorowii”, Nippon Kagaku Zasshi, 85, p.558-560, 1964. [C.A. 1965, 63,
    3314d].
    108.Yook, C. S.; Kim, H. S.; Kim, C. T. “Studies on the coumarins of the
    fruits of Peucedanum terebinthaceum Fisher et Turcz”, Yakhak Heochi, 30,
    p.73-78, 1986. [C.A. 1986, 105, 102407s].
    109.Abyshev, A. Z.; Azhdarov, B.; Gashimov, N. F. “Acetonide of oxypeucedanin
    hydrate as a new component from Peucedanum turcomanicum”, Khim. Prir.
    Soedin., 16, p.847-848, 1979. [C.A. 1980, 93, 41499h].
    110.Sun, H.; Lin, Z.; Niu, F. “Studies on the traditional Chinese drugs of
    Umbelliferae. VI. Chemical constituents of Peucedanum turgeniifolium Wolff.
    Part 2”, Yunnan Zhiwu Yanjiu, 5, p.433-436, 1983.
    111.Lin, Z.; Niu, F.; Ding, J., “Studies on Chinese herbs in Umbelliferae. II.
    New coumarins in Peucedanum turgeniifolium Wolff”, Yunnan Chih Wu Yen
    Chiu, 3, p.173-180, 1981. [ C.A. 1982, 96, 40789c].
    112.Bohlman, F; Grenz ,M. ”New butenolide derivatives from Umbelliferae.”,
    Tetrahedron Lett., 12, p.3693-26, 1971.
    113.Cisowski, W. “Flavonoid glycosides of Peucedanum verticillare L. Koch. Ex
    DC”, Herba. Pol., 30, p.159-163, 1984. [C.A. 1986, 104, 165364a].
    114.Bohlmann,F. “Coumarins from the roots of Peucedanum insolens kitagawa”,
    Chem. Ber., 94, p.958-967, 1961.
    115.Kong, L. Y.; Wu, X. L. ; Niwa, M. “Two dihydropyranocoumarins from
    Peucedanum wawrii”, Heterocycles, 60, p.599-606, 2003.
    116.Ye, J.; Zhang, H.; Yuan, C. “Studies on chemical components of Peucedanum
    wawrii (Wolff) Su”, Zhiwu Xuebao, 31, p.735-736, 1989. [C.A. 1990, 113,
    74790f].
    117.Kong, L.; Zhi, F. “Coumarins from Peucedanum wulongense”, J. Asian Nat.
    Prod. Res., 5, p.183-187, 2003. [C.A. 2003, 139, 603577].
    118.Ngwendson, J. N.; Bedir, E.; Efange, S. M. N.; Okunji, C. O.; Iwu, M. M.;
    Schuster, B. G.; Khan, I. A., “Constituents of Peucedanum zenkeri seeds
    and their antimicrobial effects”, Pharmazie, 58, p.587-589, 2003.
    119.Lemmich, J.; Lemmich, E.;Nielsen, B. E. “Constituents of Umbelliferous
    Plant”, Acta Chem. Scand, 20, p.2497-2507, 1966.
    120.Takata, M.; Shibata, S.;Okuyama, T. “Structures of angular pyranocoumarins
    of bai-hua qian-hu, the of Peucedanum praeruptorum”, Planta Med., 56,
    p.307-311, 1990.
    121.Duh, C. Y.; Wang, S. K. I.; Wu, Y. C. “Cytotoxic pyranocoumarins from the
    aerial parts of Peucedanum japonicum”, Phytochemistry, 31,p.1829-1830,
    1992.
    122.Matsuda, H.; Murakami, N. N.; Kageura, T.; Yoshikawa, M. “Medicinal
    foodstuffs. XX. Vasorelaxant active constituents from the roots of Angelica
    furiijuga Kitagawa: structures of hyuganins A, B, C, and D”, Chem. Pharm.
    Bull., 48, p.1429, 2000.
    123.Luiz, C. A. B.; Antonio, J. D.; John M. “Novel rearrangement of 2-a-
    isopropyl-8-oxabicyclo[3.2.1]oct-6-ene producting the monoterpene 3-
    hydroxyphellandral”, J. Chem. Soc. Perkin. Trans, 1, p.585-587, 1993.
    124.Swager, T. M.; Cardellina II, J. H. “Coumarins from Musineon
    divaricatum”, Phytochemistry, 24, p.805-813, 1985.
    125.Zeid, A. H. “Stress metabolites from Corchorus olitorius L. leaves in
    response to certain stress agents”, Food Chemistry, 76, p.187-195, 2002.
    126.Chen, Z. S.; Lai, J. S.; Kuo, Y. H. “The constituents of Cynanchum
    taiwanianum”, J. Chin. Chem. Soc., 38, p.393-396, 1991.
    127.Derek, H. R. B.; Lee, K. W.; Mehl, W.; Nubar O.; Li, Z. “Functionalsation
    of saturated hydrocarbons. part XVII. reactivity of carbon-carbon double
    bonds.", Tetrahedron, 46, p.3753-3768, 1990.
    128.Tilstra, L.; Sattler, M. C.; Cherry, W. R.; Barkley, M. D. “Fluorescence
    of a rotationally constrained tryptophan derivative, 3-carboxy-1, 2, 3, 4-
    tetrahydro- 2-carboline”, J. Am. Chem. Soc., 112, p.9176-9182, 1990.
    129.Tsai, F. Y.; Lee, S. S.; Chen, I. S. “Chemical Constituents from Berchemia
    formosana”, J. Chin. Chem. Soc., 42, p.101-105, 1995.
    130.Terreaux, C.; Maillard, M.; Hostettmann, K. “Structure revision of a
    furanocoumarin from Dorstenia contrajerva”, Phytochemistry, 39, p.645-647,
    1995.
    131.Wu, T. S.; Kuoh, C. S.; Wang, C. H.; Tien, H. J. “Constituents the Peel of
    Citrus depressa Hayata”, J. Chin. Chem. Soc., 31, p.307-309, 1999.
    132.Piao, X. L.; Park, I. H.; Baek, H. Y. K. “Antioxidative activity of furano-
    coumarins isolated from Angelicae dahuricae”, J. Ethnopharmacology , 93,
    p.243-246, 2004.
    133.Jimenez, B.; Grande M. C.; Anaya, J. “Coumarins from Ferulago capillaris
    and F. brachyloba”, Phytochemistry, 53, p.1025-1031, 2000.
    134.Wang, C. C.; Chen, L. G.;Yang, L. L. “Inducible nitric oxide synthase
    inhibitor of the Chinese herb I. Saposhnikovia divaricata (Turcz.)
    Schischk”, Cancer Lett, 145 , p.151-157, 1999.
    135.Xie, L.; Crimmins, M. T.; Lee, K. H. “Asymmetric synthesis of 3', 4'-Di-O-
    (-)-camphanoyl-(+)-cis-khellactone (DCK), a potent anti-HIV agent”,
    Tetrahedron Lett , 36, p.4529-4532, 1995.
    136.Lee, C. K.; Chang, M. H. “The chemical constituents from the Heartwood of
    Eucalyptus citriodora”, J. Chin. Chem. Soc. 47, p.555- 560, 2000.
    137.Terreaux, C.; Maillard, M.; Hostettmann, K. “Structure revision of a
    furanocoumarin from Dorstenia contrajerva”, Phytochemistry, 39, p.645-647,
    1995.
    138.Chen, C. Y.; Wu, T. Y., Chang, F. R.; Wu, Y. C. “Ligans and kauranes from
    the stem of Annona cherimola", J. Chin. Chem. Soc., 45, p.629-634, 1998.
    139.Frans, B.; Dirk, H. “Synthese von 1-aryl-und 1-alkenyl--carbolinen durch
    palladium-katakysierte kupplungsreaktionen”, Liebigs Ann. Chem., p.1315-
    1319, 1992.
    140.Lee., C. K.; Lu, C. K.; Kuo, Y. H. “New Prenylated flavones from the roots
    of Ficus beecheyana”, J. Chin. Chem. Soc., 51, p.437-441, 2004.
    141.Hans, A.; Harald, H.;Wolfgang, B. “Cardioactive steroid saponins and other
    constituents from the aerial parts of Tribulus cistoides”, Phytochemistry,
    35, p.1527-1543, 1994.
    142.Junichi, K.; Toru, I.; Yasuko, T.; Yoshiteru, I. “Water-soluble
    constituents of Fennel. IX. Glucides and Nucleosides”, Chem. Pharm. Bull.,
    47, p.988-992, 1999.
    143.台灣植物誌第二版編輯委員會編輯出版, “台灣植物誌”, 中華民國 台灣 台北,
    第三卷,p.696-699, 1993.
    144.邱年永;張國雄, “原色台灣藥用植物圖鑑”,台北南天書局發行, 3,p.131-132,
    1998。
    145.Park, S.; Lee, D. K.; Whang, Y. H.; Yang C. H. “Monordin I, a compound of
    Ampelopsis radix, inhibits AP-1 activation induced by phorbol ester”,
    Cancer Lett., 152, p.1-8, 2000.
    146.Yabe, N; Matsui, H. “Ampelopsis brevipedunculata (Vitaceae) extract
    inhibits a progression of carbon tetrachloride-induced hepatic injury in
    the mice”, Phytomedicine, 7, p.493-498, 2000.
    147.Yang, L. L.; Yen, K. Y.; Kiso, Y.; Hikino, H. “Antihepatotoxic actions of
    Formosan Peucedanum japonicum”, J. Ethnopharmacol., 19, p.103-110, 1987.
    148.Lee, H.; Lin, J. Y. “Antimutagenic activity of extracts from anticancer
    drugs in Chinese medicine”, Mutat. Res., 204, p.229-234, 1988.
    149.Sun, X.; Guan, Y. X.; Luo, X. L.; Yu, Y. A.; Gao, H. Z. “Observation of
    the efficacy of Ampelopsis brevipedunculata Trautv. In the treatment of
    herpes zoster”, J. Traditi. Chin. Med., 6, p.17-18, 1986.
    150.Katsuta, H.; Takaoka, T. “An attempt in tissue culture at preventing and
    treating the collagen fiber formation of liver cells”, Jap. J. Exp. Med.,
    50, p.275-282, 1980.
    151.Chen, Z.; Wang, M.; Cai, P.; Chen, X. “Determination of ampelopsin and
    myricetin in Ampelopsis cantoniensis”, Zhong Yao Cai, 20, p.23-25, 1997.
    152.王玫馨; 黃愛東 “無刺根黃酮類成分的分離和鑑定”, 中藥材, 12, p.28-29, 1987.
    153.王玫馨; 周愛群 “無刺根炮製品的質量研究”, 中藥材, 12, p.31-33, 1989.
    154.Inada, A.; Nakamura, Y.; Konishi, M.; Murata, H.; Kitamura, F. “A new
    ionone glucoside and a new phenylpropanoid rhamnoside from stem of
    Ampelopsis brevipedunculata (Maxim.) Trautv”, Chem. Pharm. Bull., 39,
    p.2437-2439, 1991.
    155.Oshima, Y.; Ueno, Y. “Ampelopsis D, E, H and cis-ampelopsin E,
    oligostilbenes from Ampelopsis brevipedunculata var. hancei roots”,
    Phytochemistry, 33, p.179-182, 1993.
    156.Oshima, Y.; Ueno, Y.; Hikino, H. “Ampelopsins A, B and C, new
    oligostilbenes of Ampelopsis brevipedunculata var. hancei”, Tetrahedron,
    46, p.5121-5126, 1990.
    157.Oshima, Y.; Ueno, Y.; Hisamichi, K.; Takeshita, M. “Ampelopsins F and G,
    novel bridged plant oligostilbenes from Ampelopsis brevipedunculara var.
    hancei roots (Vitaceae)”, Tetrahedron, 49, p.5801-5804, 1993.
    158.Wang, D.; Liu, J.; Lu, J.; Zheng, S. “Two new limonoids of Ampelopsis
    grossedentata Hand-Mazz”, Indian J. Chem. Sect. B, 38, p.240 - 242, 1999.
    159.v.Gorup-B., “Peucenidine accumulation dynamics in Peucedanum oreoselinum
    Moench”, Justus Liebigs Ann. Chem., 161, p.229, 1872.
    160.Kotake, K. “Uber Inhaltsstoffe von Ampelopsis meliaefolia Kudo(Haku-
    Tya)”, Justus Liebigs Ann. Chem, 544, p.253-254, 1940.
    161.v.Gorup-B., “Study of some representatives of the Umbelliferae family”,
    Chem. Ber., 4, p.906, 1871.
    162.Kitajima, J.; Kamoshita, A.; Ishikawa, T.; Takano, A.; Fukuda, T.; Isoda,
    S.; Ida, Y. “Glycosides of Atractylodes ovata”, Chem. Pharm. Bull., 51,
    p.1106-1108, 2003.
    163.Yu, H. J.; Chen, C. C.; Shieh, B. J. “The constituents from the leaves of
    Magnolia coco”, J. Chin. Chem. Soc., 45, p.773-778, 1998.
    164.Lee, C. K.; Chang, M. H. “The chemical constituents from the heartwood of
    Eucalyptus citriodora”, J. Chin. Chem. Soc., 47, p.555-560, 2000.
    165.Kuo, Y. H.; Chu, P. H. “Studies on the constituents from the bark of
    Bauhinia purpurea”, J. Chin. Chem. Soc., 49, p.269-274, 2002.
    166.Lee, T. H.; Hsu, F. L. “Triterpene acids from the leaves of Planchonella
    duclitan (Blanco) Bakhuizan”, J. Chin. Chem. Soc., 52, p.1275-1280, 2005.
    167.Wongsinkongman, P.; Brossi, A.; Wang, H. K.; Bastow, K. F.; Lee, K. H.
    “Antitumor agents. Part 209: Pheophorbide-a derivatives as photo-
    independent cytotoxic agents”, Bioorg. Med. Chem., 10, p.583-591, 2002.
    168.Nakatani, Y.; Ourisson, G.; Beck, J. P. “Chemistry and biochemistry of
    Chinese drug, VII. Cytostatic pheophytins from silkworm excreta, and
    derived photocytotoxic pheophorbides”, Chem. Pharm. Bull. 29, p.2261-2269,
    1981.
    169.Wolf. “On the isolation of (+)-samidin from the roots of Peucedanum
    japonicum Thunb”, Justus Liebigs Ann. Chem., 704, p.1967, 208.
    170.Cheng, K. H.; Wang, H. K. “Cytotoxic phephorbid-related compounds from
    Clerodendrum calamitosum and C. cyrtophyloum”, J. Nat. Prod., 64, p.915-
    919, 2001.
    171.Wongsinkongman, P.; Brossi, A.; Wang, H. K.; Lee, K. H. “Antitumor agents.
    Part 209: pheophorbide-a derivatives as photo-independent cytotoxic
    agents”, Bioorg. Med. Chem.10, p.583-591, 2002.

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