近年來海洋環境中的塑膠微粒 (< 5 mm) 汙染仍持續累積而增加，並且透過水產品進入食物鏈，對消費者造成健康風險。在水產品中，國民飲食習慣中常見且食用過程前不會去除腸胃道的濾食性貝類暴露風險更高。由於牡蠣可能在生活水域積聚和濃縮汙染物，因此通常會在相對乾淨的海域採集或養殖貝類，透過牡蠣的生物特性淨化 (depuration)，許多人會將牡蠣放置在乾淨的海水中，使牡蠣進行正常的濾水活動幾個小時到幾天，讓體內汙染物將低至一定程度，降低汙染帶來的致病風險，提升食品安全性。最近許多研究發現，無論是野生或養殖的牡蠣，都普遍存在塑膠微粒的汙染。本研究為了避免人類從水產品中攝入大量的塑膠微粒，以台灣南部地區養殖的葡萄牙牡蠣 (Crassostrea angulata) 為實驗材料，使用自製之不規則狀螢光塑膠微粒，探討葡萄牙牡蠣暴露於塑膠微粒後，在沒有食物供給的情況下，能否利用牡蠣淨化之特性來降低其體內塑膠微粒含量，並根據其糞便及環境中的水樣調查可能的排泄路徑。結果顯示，牡蠣暴露於每公升3050個聚苯乙烯 (polystyrene) 塑膠微粒中，兩小時後平均攝取到了252.00 ± 31.23個塑膠微粒。在為期96小時的淨化 (depuration) 過程中，於48小時即降低了78.42%的塑膠微粒。牡蠣排泄聚苯乙烯塑膠微粒為混合於糞便中排出，但隨著時間增加而呈遞減趨勢，在沒有食物供給的情況下，可能會排放至環境 (水體) 中，且可能再次循環而被牡蠣攝食。本研究顯示，在沒有食物供給的情況下，淨化仍是減少葡萄牙牡蠣中尺寸介於5~100 μm聚苯乙烯塑膠微粒的有效方法，且最有效且經濟的淨化時間為48小時，在排泄的過程中，除了混合於糞便中排出外，亦可能會回到環境中，再次被牡蠣攝入。

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