利用高穿透力的電磁輻射或是帶電粒子的幅射照射合成方法是均勻化學環境溶液中的合成反應時的有利方法。同步輻射加速器的導入使得 x-ray 產生了有著前所未有的亮度，這不僅使得以光當作偵測器的分析鑑定技術有了革命性的發展，而且也可在快速且可控制的合成反應中當作刺激源。
本論文總結了 x-ray 合成的奈米粒子具有獨特性質與優異的性能，如高膠體穩定性、單分散性、可控制的尺寸分布與乾淨的奈米粒子表面無受到來自非想要的表面反應物與反應劑的汙染。因此，這些特點導致了高分散性的高生物相容性奈米粒子有著強健表面修飾能力，特別是於生物醫學領域應用，而其中許多只有通過同步輻射加速器的合成方法才能實現。本文對同步輻射合成的基本原理，包含一般金屬、氧化物，合金及高分子的奈米粒子合成進行了廣泛且系統性的研究。對於兩種不同實驗合成的機構: 以固定式溶液與連續流動式系統，對他們之間的相似與差異性也進行了廣泛的檢驗研究，並利用極強強度的 x-ray 證實了其合成方式所具有的獨特之處
本文也簡要的論述快速的合成方法與可能量產合成的拓展性成為作為連續式流體反應系統的發明的動機。利用快速、均勻合成的化學反應特性有著許多有利特點，更進一步對該系統的完善，可以對在大型同步加速器設施中長期以來一直沒有實現並期盼已久工業化規模的化學合成生產開啟一扇窗。

Radiation synthesis methods taking advantage of the high penetration electromagnetic waves or charged particles are favorable methods when a homogeneous chemical environment in solution is required for the synthesis reaction. The addition of synchrotron to the generation of x-rays with unprecedented brightness not only revolutionized the analytical characterization technologies using light as a probe, but as a stimulation source for fast and controllable synthesis.
This thesis summarizes the x-ray synthesis of nanoparticles with unique properties and excellent performances, such as high colloidal stability, monodispersed and controllable size distribution and the clean nanoparticle surface without contamination of undesired surfactants and reaction agents. These characteristics consequently lead to highly dispersed biocompatible nanoparticles with robust surface modification were particularly favorable in biomedical applications and many of them are only possible with synchrotron synthesis. The general mechanism of synchrotron x-ray synthesis, common to the synthesis of metal, oxide and alloy and polymer nanoparticles, were extensively and systematically investigated. The similarity and the difference of the resulting nanoparticles with two different experimental synthesis configurations: the stationary solution and the continuous-flow system, were extensively examined and used to corroborate the unique features of the synthesis using extremely intense x-rays.
The very fast synthesis and the possible scaling up is briefly discussed as the motivation to invent the continuously flow synthesis. With many favorable features taking advantage of the fast and uniform synthesis chemical reactions, further perfection of this system could open a window for the industrial scale chemical synthesis which were long expected but never realized in large synchrotron facilities.

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