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研究生: 楊宗耀
Yang, Zong-yao
論文名稱: 利用超音波技術來發展膀胱容積的監測系統
Development of a Monitoring System for Bladder Volume with Ultrasound Techniques
指導教授: 陳天送
Chen, Tain-song
學位類別: 碩士
Master
系所名稱: 工學院 - 醫學工程研究所
Institute of Biomedical Engineering
論文出版年: 2009
畢業學年度: 97
語文別: 中文
論文頁數: 59
中文關鍵詞: 掃描機構膀胱容積尿路動力學檢查超音波技術
外文關鍵詞: Scanning apparatus, Ultrasound technique, Urodynamic study, Bladder volume
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  • 臨床上診斷膀胱疾病的方法,主要為尿路動力學檢查,透過此項檢查我們可以得知病人的尿流速、壓力變化與膀胱尿容量等資訊;但由於該檢查方式為侵入式、並且檢查耗費時間,且容易產生患者精神上的壓力等缺點。若使用超音波技術來測量,其優點具有非侵入性、快速、可重複使用與費用較低。
    本研究主要目的為建立一套利用超音波技術套搭配掃描機構來量測膀胱容積和膀胱形狀的系統。在系統驗證方面,首先我們量測水球容積,模擬膀胱假體的情況;根據計算結果發現,其平均誤差為10.11ml,再來利用線性迴歸來分析來觀察具有高度相關性(R2=0.998)。在測量離體豬膀胱的容積方面,誤差變化為12.06±4.36ml,也具有高度相關性(R2=0.995)。透過輪廓辨識待測物的形狀,再套用適當的公式計算容積,結果與文獻中所用的方法比較,具相當高的準確率(p<0.05),平均誤差為8.5%。由統計結果顯示,非侵入式的超音波量測系統,具有臨床診斷的潛力,未來可提供醫師作為膀胱檢查的一項利器。

    The gold standard for diagnosing of bladder disease is urodynamic study. We could measure the urine flow rate, pressure and bladder volume with this test. But patient will suffer from invasive procedure, time consuming and psychological stress. Ultrasound measurements are noninvasive, rapid, reproducible and inexpensive. The aim of this study is to apply ultrasound technique to develop a scanning apparatus for measuring bladder volume and bladder shape. In the beginning, we measured the balloon volume to verify the accuracy of our system. The result showed that the mean error was 10.11ml and with high correlation coefficient (R2=0.998) by linear regression. The error variance of measuring bladder volume was 12.05±4.36ml and correlation coefficient was 0.995. Utilize the contour to recognize the shape of phantom and then apply the appropriate formula to calculate the volume. The result comparison with the literatures had high rate of accuracy (p<0.05). The results of this study indicated that the ultrasound technique is potential for measuring bladder volume noninvasively.

    目錄 中文摘要…………………………………………………………………I 英文摘要…………………………………………………………………II 誌謝………………………………………………………………………III 目錄………………………………………………………………………IV 圖目錄索引………………………………………………………………VI 表目錄索引………………………………………………………………IX 第一章 緒論………………………………………………………………1 第1-1節 膀胱解剖之構造………………………………………………1 第1-2節 膀胱簡述………………………………………………………3 第1-3節 臨床膀胱診斷方法與簡介……………………………………4 第1-4節 文獻回顧………………………………………………………5 第1-5節 研究動機與目的………………………………………………10 第1-6節 論文架構………………………………………………………11 第二章 研究原理與材料…………………………………………………12 第2-1節 超音波簡介……………………………………………………12 第2-1-1節 聲波特性……………………………………………………12 第2-1-2節 超音波掃描方式……………………………………………12 第2-2節 超音波參數……………………………………………………14 第2-2-1節 單探頭超音波參數的量測原理……………………………14 第2-2-2節 雙探頭超音波參數的量測原理……………………………15 第2-3節 超音波軸向解析度……………………………………………16 第2-4節 修正係數………………………………………………………17 第2-5節 軸向長度計算…………………………………………………18 第2-6節 超音波量測截面輪廓資訊……………………………………19 第2-7節 實驗材料………………………………………………………22 第三章 系統架構與實驗流程……………………………………………24 第3-1節 實驗架構………………………………………………………25 第3-2節 硬體詳述………………………………………………………26 第3-2-1節 超音波Pulser/Reciver & A/D card………………………26 第3-2-2節 超音波探頭…………………………………………………29 第3-2-3節 水平儀………………………………………………………31 第3-2-4節 旋轉式機構…………………………………………………32 第3-3節 離體膀胱處理…………………………………………………35 第3-4節 軟體資料分析流程……………………………………………36 第四章 實驗結果與討論…………………………………………………37 第4-1節 假體截面輪廓與容積量測……………………………………37 第4-1-1節 節假體截面輪廓……………………………………………37 第4-1-2節 水球容積量測………………………………………………40 第4-2節 使用修正係數之容積評估……………………………………43 第4-3節 膀胱容積量測…………………………………………………49 第五章 結論與未來展望…………………………………………………53 第5-1節 結論……………………………………………………………53 第5-2節 未來展望………………………………………………………55 參考文獻…………………………………………………………………56

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