牙科汞齊合金是由汞與銀、銅、錫合金粉末混製而成。除了作後咬合齒綴補材之外，亦可作根管治療後的填補，單一假牙以及牙根等應用。由於有性能優良、價格低廉、容易操作，使用年限長等優點，因此被廣泛的使用。
本實驗研究在單成分汞齊合金中，加入定量的鈀與球磨粉末，作汞釋出、機械性質的量測與比較，並且也作了包括細胞毒性、血球溶解性、潛在突變活性的體外生物相容性測試。
實驗結果顯示，在顯微觀察方面，本實驗使用的汞齊合金，由γ1相、η′相、和未反應完的γ相和ε相所組成。有添加球磨粉末的汞齊合金的η′相會變得比無添加球磨粉末的粗大。添加球磨粉末的汞齊合金汞釋出會降低。機械性質方面，添加球磨粉末的汞齊合金徑向抗拉強度較低，潛變量也明顯比不添加球磨粉末的高。但經過冷熱循環後，添加球磨粉末的汞齊合金變化幅度較小。在體外生物相容性測試方面，所有的汞齊合金都通過細胞毒性測試、血球溶解性試驗與潛在突變活性試驗，符合美國國家標準局及美國牙科協會所製訂的41號規範-牙科材料的生物性評估。

Dental amalgam is mixed with mercury by silver, copper, tin alloy powder . In addition to gear up for restorative material besides treatment for root canal restorative, applications such as single crown and fang restorative. Because of excellent performance, low cost, easy operation, long service life, etc., it is widely used.
Experimental Study of the single composition amalgam, by adding quantitative palladium powder and ball milled alloy powder for mercury vapor release, mechanical properties measurements and comparison, and also include cell toxicity assay, hemolysis assay, Ames test in vitro biocompatibility test.
The results showed that in the microscope, the amalgam were composed of γ1 phase, γ phase, η ' phase, and ε phase. After adding the ball milled alloy powder in the amalgam, the size of η ' phase area became larger. The mercury vapor release rate from amalgam containing milled powder will be reduced. The amalgam containing ball milled powder had the lower diametral tensile strength . However, after thermal cycles, the amalgam containing ball milled alloy powder had smaller change. In vitro biocompatibility tests, all of the amalgam alloy through cell toxicity test, hemolysis assay and the Ames test, in line with the American National Standards Board and the American Dental Association develop specification of 41 - Dental assessment of the biological materials.

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