中風會造成肢體運動功能喪失、語言障礙、感覺喪失等後遺症，透過復健可對神經系統產生誘發，使大腦受到損傷的鄰近區域活化並取代損傷部位，進而恢復其功能。
本研究以本實驗室發展的腦機介面(Brain Computer Interface，BCI)結合肩肘復健機器人系統，改良現有之BCI系統。為測試其功能與療效，招募兩位常人與一位中風病患進行8週的訓練，結果顯示常人受測者(N1)想像準確率隨訓練時間上升，最高可達75%，而想像時間會隨訓練縮短，最短可達4.5秒；另一位常人受測者(N2)想像準確率雖然沒有提升，但想像時間一樣隨訓練而縮短，最短可達5秒。中風病患(S1)的想像準確率有顯著上升，患側最高可達65%、健側最高為75%。想像時間患側最短為5秒、健側最短為4.5秒。訓練後的傅格-梅爾評估(Fugl-Meyer Assessment，FMA)與修正式艾許瓦氏量表(Modified Ashworth Scale，MAS)臨床指標顯示皆有進步，且功能性磁振造影(functional MRI，fMRI)結果顯示訓練後腦部運動感覺區有集中活化的現象。
本研究證實改良過後的BCI系統對於腦波辨識更為精準，且新的復健訓練技術對於中風病患復健治療更為有效。唯未來仍然需要招募更多中風病患進行測試，以提升其可信度。

Stroke causes some sequelae such as loss of unilateral motor function, speech impairment and loss of sensation. Rehabilitation can induce the central nervous system to replace the function of lesion parts with the nearby unaffected parts.
This study combines an EEG-based BCI system which integrated with a shoulder-elbow robot. Two healthy subjects and a stroke patient were recruited to participate in the training of using the modified BCI system for 8 weeks. One of the healthy subjects (N1) can trigger the robot in 4.5 seconds and the highest accuracy is 75%. After the training, the overall trend of accuracy is increasing and the overall trend of trigger time is decreasing. The other (N2) can trigger the robot in 5 seconds, the overall trigger time is decrease but the overall accuracy isn’t changed significantly. However, the stroke patient (S1) has significant change of the accuracy. The affected side has the shortest trigger time of 5 seconds and the highest accuracy is 65%. The unaffected side has the shortest trigger time of 4.5 seconds and the highest accuracy reaches 75%. After training, the patient’s FMA and MAS improved, and the result of fMRI shows the reorganization does occur and concentrate on primary motor cortex. It shows that the new rehabilitation training can be better than previous protocol.
This study indicates the modified BCI system is more accurate for the EEG feature identification and the new rehabilitation training is better than previous one. More stroke subjects are needed to validate the preliminary results of this study.

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