本研究從空間知識動態的角度，建構一套能描繪區域創新系統 (Regional Innovation System, RIS) 長期演化的分析模式。既有 RIS 相關研究多著重於主體結構、制度安排或網絡連結，較少探究系統內知識在不同時期如何被應用、吸收與轉化，也難以解釋不同RIS之間的差異。因此，本研究立基於既有理論，將知識動態操作化為四項功能：知識應用、知識探勘、知識生成與知識擴散，作為建立演化模式的基礎。
經由理論梳理，本研究以模糊德爾菲與模糊層級分析法進行兩階段專家問卷，以確認四項知識功能中的具體指標及其相對重要性，並搭配敘述統計與深度訪談，從產業結構、主體組成、制度條件與知識連結等面向，分析新竹科學園區與南部科學園區及其周邊地區的演化歷程。
研究結果指出，RIS確實具有演化特性，且四項知識功能會隨產業生命週期、制度安排與外部知識來源而調整。竹科自早期便因明確的技術需求而同時展現探勘與應用活動，並在累積中逐步強化知識生成能力，形成以積體電路產業為核心、具高度外溢效果的創新環境。相較之下，南科在初期受政策導向較強，產業以生產導入與在地擴散為主，知識生成能量相對有限；直到近年先進製程投資逐步到位後，其生成活動才明顯提升。兩者在背景條件、制度與產業結構的差異，使其呈現截然不同的知識動態與演化路徑。
本研究提出的演化模式，可補足 RIS 研究在長期描繪上的不足，並說明不同區域在不同政策與產業脈絡下，如何形成差異化的知識動態結構。面對全球生產網絡重組與供應鏈外移的新趨勢，研究也指出，相較於僅聚焦產線移動或成本因素，更重要的是強化海外與我國間的知識回流，包括跨區域研發合作、人才流動、海外在地知識的蒐集與轉譯，以及提升園區的吸收能力，使海外布局反而能成為深化國內RIS的重要契機。
整體而言，本研究建構一套具知識動態概念的 RIS 演化模式，不僅能解析竹科與南科的異質性發展，也可作為後續比較研究與政策規劃的分析基礎。

This dissertation examines the evolution of regional innovation systems through the concept of territorial knowledge dynamics, using Hsinchu Science Park and Southern Taiwan Science Park as comparative cases. By integrating global production networks, territorial knowledge dynamics, and regional innovation systems, this study constructs an analytical framework based on four knowledge functions: knowledge application, knowledge exploitation (with (with explorative extension), knowledge generation, and knowledge diffusion. The findings show that the two science parks have followed different evolutionary paths due to differences in institutional conditions, industrial structures, historical trajectories, and knowledge bases. Hsinchu Science Park demonstrates stronger knowledge generation and diffusion capacities, while Southern Taiwan Science Park has developed through knowledge application, production expansion, and later-stage functional upgrading. This study argues that successful regional innovation systems cannot be simply replicated; rather, they must be understood through their specific knowledge functions, territorial contexts, and evolutionary processes.

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