| 研究生: |
張恩旗 Chang, En-Chi |
|---|---|
| 論文名稱: |
毛細力驅動流體晶片的設計和混合應用 A study on the design and mixing application of the capillary driven fluidic chip |
| 指導教授: |
鍾震桂
Chung, Chen-Kuei |
| 學位類別: |
碩士 Master |
| 系所名稱: |
工學院 - 奈米科技暨微系統工程研究所 Institute of Nanotechnology and Microsystems Engineering |
| 論文出版年: | 2010 |
| 畢業學年度: | 98 |
| 語文別: | 中文 |
| 論文頁數: | 105 |
| 中文關鍵詞: | 微混合器 、毛細力幫浦晶片 |
| 外文關鍵詞: | micromixer, capillary pump chip |
| 相關次數: | 點閱:145 下載:0 |
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實驗室晶片是生醫檢測一直想發展的部份,生醫檢測除了要精確之外,還希望達到輕、薄、短、小、節省檢測時間、節省檢測試劑與檢體等目的,毛細力的驅動恰好符合這些需求,靠著材料本身的親水性推動流體,所以不用外加推動系統,JSR光阻與玻璃本身就是親水性材料,且親水性不隨時間衰弱。
本研究針對矩形流道的毛細作用做探討,從理論開始著手,討論親斥水性材質與流道幾何等參數對流動的影響,然後配合實驗互相比較,提供設計混合晶片的依據。
最後提出兩種製程來製作混合晶片-雙面膠玻璃晶片與JSR光阻玻璃晶片,這兩種晶片都具有上述優點。在此使用擋版結構來增加其混合的效果,這兩種晶片只需簡單的雷射加工與黃光製程就可以製作,不需要蝕刻與沉積等等的程序,在混合效果方面也相當不錯。希望未來可以與生醫檢測整合,做出可以商品化的檢測晶片。
Lab on chip is very significant study in biology test system. In addition to accuracy, we hope the chips are slight, thin, small, time saving and reagent saving. The capillary force driving system conforms to these requirements because of the fluid is driven by the hydrophilic material without external force.
In our research, both hydrophilic property of JSR photoresist and glasses don’t decay with time are utilized under micro rectangle channels system by capillary force driving. First, we discuss the effect of channel geometry and hydrophilic material on micro fluid field. Then, we compare the theory with experiments to get the best design of channels.
Finally, two kinds of micromixer named JSR-glass micromixer and doubleside tape-glass micromixer are fabricated which both have the above advantages. Here, baffles are used to be the mixing structure for enhancing the mixing efficiency. These chips have a good mixing efficiency fabricated easily by photolithography and laser ablation without etching and deposition process. We hope our chip can be utilized in practical bio-test filed.
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校內:2020-12-31公開