本論文第一部分將沉積於網版印刷碳電極(SPCE)上之氧化石墨烯-奈米碳管(GO-CNT)電化學還原成三維之還原氧化石墨烯-奈米碳管(rGO-CNT)，製得rGO-CNT/SPCE，用於有機磷農藥(巴賽松)之非酵素電化學偵測。奈米碳管的存在可導致三維結構的形成，使rGO的表面積可被更有效的用於巴賽松的吸附與感測，以改善其靈敏度。結果證實，奈米碳管確實均勻的分散在GO表面，且GO已成功利用電化學還原法還原為rGO。rGO-CNT/SPCE用於巴賽松的電化學偵測係在pH 7.0之0.1 M磷酸鹽緩衝溶液中以微分脈衝伏安法(DPV)進行，結果顯示巴賽松濃度之線性範圍為0.005~5 μM，偵測極限則為0.002 μM。而在真實水樣品與干擾物測試之結果，rGO-CNT/SPCE亦展現良好之性能，顯示其確可作為良好的電化學偵測平台，有效地應用於有機磷農藥的偵測與環境監控。
在第二部分研究中，將檸檬酸與β-環糊精(βCD)於200oC下直接加熱製得粒徑約9 nm之βCD修飾石墨烯量子點 (βCD-GQD)，用於毒性有機汙染物的螢光偵測。結果發現，βCD修飾可顯著提升GQD的螢光強度，且用於硝基苯酚的螢光偵測時，在0.1~7.5 μM及7.5~100 μM兩段濃度範圍具有良好的線性關係，偵測極限為0.093 μM。此性能明顯較無βCD修飾之石墨烯量子點為佳，顯示所發展之βCD-GQD在螢光偵測確實具有應用潛力。

Firstly, three-dimensional (3D) reduced graphene oxide-carbon nanotube (rGO-CNT) nanocomposite was fabricated via the electrochemical reduction of graphene oxide-carbon nanotube (GO-CNT) on the screen printed carbon electrode (SPCE) to yield the rGO-CNT/SPCE for the electrochemical detection of phoxim. The presence of carbon nanotubes (CNTs) could lead to the formation of 3D structure, making the surface area of rGO can be utilized more efficiently to improve the sensitivity. It was demonstrated that CNTs were uniformly dispersed on GO, and GO has been electrochemically reduced to rGO. The electrochemical detection of phoxim on rGO-CNT/SPCE was performed in 0.1 M phosphate buffer at pH 7.0 by differential pulse voltammetry. A linear concentration range of 0.005~5 μM with a limit of detection (LOD) of 0.002 μM was obtained. For the detection of real samples and interference test, rGO-CNT/SPCE also exhibited an excellent performance. This revealed that it indeed could be used for the electrochemical detection and environmental monitoring of organophosphate pesticides. Secondly, β-cyclodextrin-modified graphene quantum dots (βCD-GQD) of about 9 nm were synthesized by the direct heating of citric acid and βCD at 200oC for the fluorescent detection of p-nitrophenol. The modification with βCD could significantly enhance the fluorescence intensity of GQD. Furthermore, for the fluorescent detection of by βCD-GQD, two linear concentration ranges of 0.1~7.5 μM and 7.5~100 μM with a LOD of 0.093 μM were obtained. The performance was significantly better than the un-modified GQD, revealing the resulting βCD-GQD indeed could be utilized in the fluorescent detection of toxic organic contaminants.

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