鈴木草屬在分類地位上為唇形科(Lamiaceae)，屬東亞特有植物，僅分佈於台灣及日本琉球群島，為多年生草本，具匍匐莖，葉寬卵形，粗鋸齒緣，腋生疏散總狀花序，密被腺毛，唇瓣花，色紫豔，具蜜腺，蜜蜂等昆蟲為其主要之傳粉媒介；全世界一屬兩種，目前被世界保育組織IUCN (The world conservation union)列為瀕臨滅絕之稀有植物。本研究以葉綠體 DNA 之trnD-trnT 基因間之
非轉譯區間(non-coding spacer)片段與合成甘油三磷酸脫氫酵素 G3PDH(glyceraldehyde-3-phosphate dehydrogenase) 基因片段為遺傳標示物來探討鈴木草屬間的親緣地理關係。根據兩遺傳標示物之結果顯示，鈴木草屬具高的遺傳歧異度；在葉綠體DNA 所建構之親緣演化樹狀圖中，鑑定出兩演化支系，其中一支系包含大部分的台灣鈴木草族群，而另一支系則由所有的琉球鈴木草族群及台灣鈴木草的金馬隧道族群組成，然而細胞核DNA 演化樹狀圖中金馬隧
道族群與其他台灣鈴木草族群群聚，顯現金馬隧道族群可能為以琉球鈴木草為母系，以台灣鈴木草為父系起源之種間雜交。台灣鈴木草因海拔環境差異分成山系族群與沿海族群，此二族群顯示高度遺傳分化；相對地，嶼那國島之琉球鈴木草族群間則具頻繁基因交流，但族群間不符合isolation-by-distance 模式。根據葉綠體DNA 所構築的親緣網狀圖(minimum spanning network)顯示嶼那國
島琉球鈴木草族群與台灣鈴木草之低海拔族群擁有較古老祖先型，依據分子時鐘(molecular clock)推估，分布於低海拔的台灣鈴木草與琉球鈴木草之共同祖先，於距今約一百一十萬年前分別進入琉球群島及台灣後分歧並種化。台灣鈴木草的種化伴隨族群向高海拔地區之輻射適應，而造成山系與海系之族群分化。綠島之琉球鈴木草的拓殖約發生在距今九十三萬年前。相對於葉綠體DNA顯現台灣鈴木草與琉球鈴木草為二個單系群(金馬隧道族群除外)，G3PDH 基因
片段因受制衡性選擇(balancing selection)影響，種及族群皆程現paraphyly，此外，台灣鈴木草、綠島之琉球鈴木草及嶼那國島之琉球鈴木草之異基因合子(heterozygote)比例各為0.8、0、0.2。

　　Suzukia Kudo, a genus of the Lamiaceae with two species, is endemic to Taiwan (S.shikikunensis Kudo) and the Ryukyu Islands (S. luchuensis Kudo). Plants of Suzukia are perennial herbs, with long-creeping stems. Inflorescences of short or elongated racemes possess showy flowers that attract pollinators, mostly honey bee, to visit. Due to its limited population number and size, Suzukia has been listed as an endangered taxon by IUCN. In
this study, we investigated the genetic structure and hylogeographic pattern of the genus Suzukia based on the sequences of the trnD-trnT noncoding spacer of the chloroplast DNA and G3PDH (glyceraldehyde-3-phosphate dehydrogenase) gne of the nuclear DNA. In both genes high levels of genetic diversity were detected in Suzukia. Chloroplast DNA genealogy identified two lineages, one exclusively consisting of most populations of S.shikikunensis, while the other containing S. luchuensis and the Chinma population of S.shikikunensis. Nevertheless, the Chinma population is phylogenetically close to S.shikikunensis in the nuclear DNA phylogeny, indicating a hybrid origin of this population.In S. shikikunensis, populations of mountain areas were significantly differentiated from the coastal populations of Taiwan. In contrast, there existed frequent gene flow between subpopulations of Yonaguni Island. In the cpDNA minimum spanning network, coastal populations of S. shikikunensis and S. luchuensis possessed ancestral polymorphisms.Based on a molecular clock, splitting from a hypothetical common distributed at low elevations may have occurred about 1.1 million years ago. Speciation followed in Taiwan and Ryukyus, respectively. Coupled with peciation, adaptive radiation to middle and high
elevations may have led to high levels of genetic diversity in S. shikikunensis. The colonization of S. luchuensis in Green Island was dated to 0.93 million years ago. In contrast to chloroplast DNA data, G3PDH gene represent paraphyly of species and populations of the both species due to effects of balancing selection. In addition, the heterozygote ratio of S. shikikunensis, S. luchuensis in Green Island and in Yonaguni were 0.8, 0 and 0.2, respectively。

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