本研究使用微分掃描熱卡計(DSC)、偏光顯微鏡(POM)、掃描式電子顯微鏡(SEM)、原子力顯微鏡(AFM)以及廣角X光繞射儀(WAXD)來探討兩成份摻合系統poly(ethylene oxide)/low-molecular weight poly(L-lactic acid) (PEO/LMw-PLLA)的相容性以及球晶型態。此兩成份混摻系統，於熔融態呈現均勻相型態，此外，LMw-PLLA的平衡熔點隨PEO加入而下降且作用力參數(12)為-0.65，證明此摻合系統為一相容系統。
相較於neat LMw-PLLA，當混系統中的PEO含量低於50 wt%時，且結晶溫度為105 oC~135 oC時，LMw-PLLA成長速率增加；然而，當混系統中的PEO含量大於80 wt%時，LMw-PLLA的球晶成長速率則降低。Neat LMw-PLLA於Tc=125~130 oC時會產生具有環狀消光環的球晶(ring-band spherulites)，然而與PEO混摻後，形成環狀帶球晶的溫度範圍為Tc=110~130 oC。由AFM的結果，LMw-PLLA的環狀消光環球晶中的ridge 及valley處，主要分別由edge-on及flat-on的晶板構成。此外，neat LMw-PLLA及PEO/LMw-PLLA系統結晶後，於降溫過程中會產生裂縫(cracks)，而其形貌主要受球晶型態、結晶溫度以及PEO的含量影響。

Miscibility and spherulitic morphology of poly(ethylene oxide)/low-molecular-weight poly(L-lactic acid) (PEO/LMw-PLLA) blends were studied using differential scanning calorimeter (DSC), polarized-light microscopy (POM), scanning electron microscopy (SEM), atomic force microscopy (AFM), and wide-angle X-ray diffractometer (WAXD). The PEO/LMw-PLLA blend is a miscible blend with a interaction parameter (12) = -0.65.
Compared with the growth rate of neat LMw-PLLA at crystallization temperature 105 oC~135 oC, that of LMw-PLLA in blend system increases with increasing PEO content up to 50 wt% and decreases when PEO content is higher than 80 wt%. Neat LMw-PLLA shows ring-banded spherulites at Tc=125~130 oC, but in the miscible PEO/LMw-PLLA blend, LMw-PLLA shows ring-banded ones at Tc’s (110 ~ 130 oC). In addition, the ring-banded patterns in the blend samples at the same Tc become regular. The AFM characterizations on the ring-banded spherulite of blend show that the ridge and valley regions of ring bands consist of edge-on and flat-on lamellae, respectively. After cooling from Tc to ambient temperature, the cracks are formed in the spherulite, and the crack patterns are influenced by spherulite morphology, crystallization temperature, and PEO content.

1.Paul, D. R.; Newman, S.; EDs. Polymer Blends; Academic Press: New York, 1978; Vols. 1, 2.
2.Bank, M.; Leffingwell, J.; Thies, C. Macromolecules, 1971, 6, 43.
3.Nishimoto, M.; Keskkula, H.; Paul, D. R. Polymer, 1991, 32, 272.
4.Walsh, D. J.; Higgins, J. S.; Maconndchie, A.; “Polymer Blends and Mixtures”, Mijhoff Publishers, Boston, 1985.
5.Landry, C. J. T.; Yang, H.; Machell, J. S. Polymer, 1991, 32, 44.
6.Coleman, M. M.; Moskala, E. J. Polymer, 1983, 24, 251.
7.Varnell, D. F. Moskala, E. J.; Painter, P. C.; Coleman, M. M. Polym. Eng. Sci. Phys. Ed., 1983, 23, 658.
8.Eisenberg, A.; Hara, M. Polym. Eng. Sci., 1984, 24, 1306.
9.Aubin, M.; Bedard, Y.; Morrissette, M. F.; Prud’homme, R. E. J. Polym. Sci. Phys. Ed., 1983, 21, 233.
10.Rodriguez-Parada, J. M.; Percec, V. Macromolecules, 1986, 19, 55.
11.Lu, J. M.; Qiu, Z. B.; Yang, W. T. Polymer, 2007, 48, 4196.
12.Tokiwa Y.; Suzuki T.; J. Appl. Polym. Sci., 1981, 26, 441.
13.Qiu, Z.; Ikehara,T.; Nishi, T. Macromolecules, 2002, 35, 8251.
14.Urayama, H.; Kanamori, T.; Kimura, Y. Macromol. Mater. Eng., 2001, 286, 705
15.Jorda, R.; Wilkes, G. L. Polym. Bull., 1988, 20, 479.
16.Tsuji, H.; Ikada, Y. Macromolecules, 1992, 25, 5719.
17.Tsuji, H.; Ikada, Y. J. Appl. Polym. Sci., 1995, 58, 1793.
18.Tsuji, H.; Ikada, Y. Polymer, 1996, 37, 595.
19.Tsuji, H.; Ikada, Y. J. Appl. Polym. Sci., 1997, 63, 855.
20.Tsuji, H.; Ikada, Y. Polymer, 1999, 40, 6699.
21.Yamane, H.; Sasai, K. Polymer, 2003, 44, 2569.
22.Tsuji, H.; Fukui, I. Polymer, 2003, 44, 2891.
23.Urayama, H.; Kanamori, T.; Fukushima, K.; Kimura, Y. Polymer, 2003, 44, 5635.
24.Blmm, E.; Owen, A. J. Polymer, 1995, 36, 4077.
25.Focarete, M. L.; Scandola, M.; Dobrzynski, P.; Kowalczuk, M. Macromolecules, 2002, 35, 8472.
26.Nijenhuis, A. J.; Colstee, E.; Grijpma, D. W.; Pennings, A. J. Polymer, 1996, 37, 5849.
27.Desai, N. P.; Hubbell, J. A. Biomaterials, 1991, 12, 144.
28.Desai, N. P.; Hubbell, J. A. Macromolecules, 1992, 25, 226.
29.Susan Budavari “The Merck index: an encyclopedia of chemicals, drugs, and biologicals”, 11th Ed, Merck & Co, Inc., Rahway, N.J., 1989.
30.Nakafuku, C.; Sakoda, M. Polym. J., 1993, 25, 909.
31.Rozema, F. R.; de Bruijn, W. C.; Bos, R. R. M.; Boering, G.; Nijenhuis, A. J.; Pennings, A. J. Adv. Biomaterials, 1992, 10, 349.
32.Bergsma, J. E.; Rozema, F. R.; Bos, R. R. M.; de Bruijn, W. C.; Boering, G.; Pennings, A. J. Biomaterials, 1995, 16, 267.
33.B. Morra; R. S. Stein J. Polym. Sci. B, 1982, 20, 2261.
34.Nojima S.; Watanabe K.; Zheng Z.; Ashida T. Polym. J., 1988, 20, 823.
35.Keith, H. D.; Padden, F. J., Jr.; Russell, T. P. Macromolecules, 1989, 22, 666.
36.Wang, Z.; Jiang, B. Z. Macromolecules, 1997, 30, 6223.
37.Wang, Z.; Wang, X.; Yu D.; Jiang. B. Z., Polymer, 1997, 38, 5897.
38.Wang, Z.; Wang, X.; An L.; Jiang, W.; Jiang, B.; Wang, X. J Polym. Sci. Part B: Polym. Phys., 1999, 37, 2682.
39.Li, W.; Yan, R.; Jiang, X.; Jiang, B. Macromol. Sci. Phys., 1992, B31, 227.
40.Wang, Z.; An, L.; Jiang, B.; Wang, X. Macromol. Rapid Commun., 1998, 19, 131.
41.Tanaka, H.; Hayashi, T.; Nishi, T.; J. Appl. Phys., 1986, 59, 3627.
42.Keith, H. D.; Padden, F. J., Jr. Polymer, 1984, 25, 28.
43.Keller, A. J. Polym. Sci. 1955, 17, 291.
44.Keller, A. .J Polym. Sci. 1959, 39, 151.
45.Keith, H. D.; Padden, F. J., Jr. Macromolecules 1996, 29, 7776
46.Keith, H. D. Polymer 2001, 42, 9987.
47.Vasanthakumari, R.; Penning, A. J. Polymer 1983, 24, 175.
48.Sarasua, J. R.; Prud’homme, R. E.; Wisniewski, M.; Le Borgne, A.; Spassky, N. Macromolecules 1998, 31, 3895.
49.Gazzano, M.; Forcarete, M. L.; Riekel, C.; Scandola, M. Biomacromolecules 2004, 5, 553.
50.Xu, J.; Guo, B. H.; Zhou, J. J.; Li, L.; Wu, J.; Kowalczuk, M. Polymer 2005, 46, 9176.
51.Yasuniwa, M.; Tsubakihara, S.; Iura, K.; Ono, Y.; Dan, Y.; Takahashi, K. Polymer 2006, 47, 7554.
52.Wang, Y.; Funari, S. S.; Mano, J. F. Macromol. Chem. Phys. 2006, 207, 1262.
53.Barham, P. J.; Keller, A. J. Polym. Sci., Polym. Phys. Ed., 1986, 24, 69.
54.Martinez-Salazar, J.; Sanchez-Cuesta, M.; Barham, P. J.; Keller, A. J. Mater. Sci. Lett., 1989, 8, 490.
55.Hobbs, J. K.; McMaster, T. J.; Miles, M. J.; Barham, P. J. Polymer, 1996, 37, 3241.
56.Xu, J.; Guo, B. H.; Chen, G. Q.; Zhang, Z. M. J. Polym. Sci., Part B: Polym. Phys., 2003, 41, 2128.
57.Kuboyama, K.; Ougizawa, T. Polym. J., 2008, 40, 1005.
58.Fraschini, C.; Plesu, R.; Sarasua, J. R.; Prud’homme, R. E. J. Polym. Sci., Part B: Polym. Phys., 2005, 43, 3308.
59.He, Y.; Fan, Z.; Wei, J.; Li, S. Polym. Eng. Sci., 2006, 46, 1583.
60.Rameau, A.; Gallot, Y.; Farnoux, P. M. B. Polymer, 1989, 30, 386.
61.Stoelting, J.; Karasz, F. E.; MacKnight, W. J. Polym. Eng. Sci., 1970, 10, 133.
62.Flory, P. J. J. Am. Chem. Soc., 1965, 86, 1833.
63.Flory, P. J. Discuss Faraday Soc., 1970, 49, 7.
64.Jo, W. H.; Lee, S. C. Macromolecules, 1990, 23, 2261.
65.Sperling, L. H. “ Introduction to Physical Polymer Science 2nd ed.”, John Wiley & Sons, Inc., New York, 1992.
66.Hudson, S. D.; Davies, D. D.; Lovinger, A. J. Macromolecules, 1992, 25, 1759.
67.Di Lorenzo, M. L. Prog. Polym. Sci., 2003, 28, 663.
68.Nakafuku, C. Polym. J., 1996, 28, 568.
69.Minakov, A. A.; Mordvintsev, D. A.; Schick, C. Polymer, 2004, 45, 3755.
70.Papageorgiou, G. Z.; Bikiaris, D. N. Polymer, 2005, 46, 12081.
71.Pan P.; Kai W.; Zhu B.; Dong, T.; Inoue, Y. Macromolecules, 2007, 40, 6898.
72.Alfonso, G. C.; Russel, T. P. Macromolecules, 1986, 19, 1143.
73.Martuscelli, E.; Silvestre, C.; Gismondi, C. Makromol. Chem., 1985, 186, 2161.
74.Keith, H. D.; Padden, F. J., Jr. J. Appl. Phys., 1964, 35, 1270.
75.Keith, H. D.; Padden, F. J., Jr. J. Appl. Phys., 1964, 35, 1286.
76.Keith, H. D.; Padden, F. J., Jr. J. Appl. Phys., 1963, 34, 2409.
77.Kawai, T.; Rahman, N.; Matsuba, G.; Nishida, K.; Kanaya, T.; Nakano, M.; Okamoto, H., Kawada, J.; Usuki, A.; Honma, N.; Nakajima, K.; Mastsuda, M. Macromolecules, 2007, 40, 9463.
78.Zhang, J.; Tashiro, K.; Tsuji, H.; Domb, A. J. Macromolecules, 2008, 41, 1352.