本研究旨在架設一套以馬達為驅動力之脈動複製裝置，以模擬自然人體之脈動血液循環系統，此裝置可用以測量人工心瓣（Artificial Heart Valve）或左心室輔助器（Left Ventricular Assist Devices, LVAD）之脈動流場狀況及其效能，並藉由量測結果來修正設計上的缺點。本脈動複製器（Pulse Duplicator）將血液循環系統分成：模擬心臟跳動之脈動器（Pulse Generator）、模擬血液在血管中流動所造成的阻抗（Resistance），及模擬血管彈性壁之順容（Compliance）等三個部分。其中，脈動器是由直流馬達（DC Motor）與齒輪泵（Gear Pump）所組成。本研究依據RCLRC等效電路來近似人類真實血液循環，因此在實驗設備上利用了兩組阻抗、兩組順容，及控制流道管徑與長度來進行模擬。本實驗是以開迴路控制馬達來達到近似人體主動脈壓與心室壓力波形；並以法蘭克-史達林定律（Frank-Starling Law）之心室壓力與體積關係配合閉迴路控制來達成模擬真實心臟脈動。研究結果顯示，本實驗可利用此一開迴路系統製造出與人體主動脈壓及心室壓力相似之壓力波形，然而當電腦輸入指令給馬達後，則需經200ms後才會有壓力訊號伴隨產生；此外，在閉迴路系統方面，本設備因脈動器收縮瞬間無法在所需壓力下產生足夠流量，因此造成目前所設計之系統尚無法模擬真實心臟脈動。其主要理由推測乃導因於本裝置管路長度過長，造成高壓差低流量，若將設備館路長度縮短應可有效解決此一問題。

　　The main purpose of this present research is to design a controllable motor-driven device, named pulse duplicator, with the function of duplicating the pulsatory mechanism in the human body. This device can be applied to evaluate the flow quality of artificial heart valves and left ventricular assist devices. Three major components, pulse generator, resistance and compliance chamber, are combined for constructing this device. Pulse generator can reproduce the similar pulse of natural heart, and is made up by a DC motor and a gear pump. Compliance chamber has the function to mimic the flexibility of real blood vessel. In this experiment, RCLRC circuit is adopted, so that there are two resistances and two compliances with fix geometric flow path are arranged. To obtain the similar pressure wave forms in aorta and ventricle, an open loop motor controller and a close loop controller with Frank-Starling law are demonstrated in this research. It is shown that the similar pressure wave forms in aorta and ventricle can basically be reproduced using the designed open loop controller. However, the test result also shows that there are 200ms delay between the input commend and the actual pressure output. In the other experiment for the close loop controller, it can be found that our system is still unable to achieve the Frank-Starling law with 100% success. The possible reason is that our pulse generator can not provide sufficient flow rate in a very short period, and it may be caused by the pipeline too long in length on device, cause the bad low flow of high pressure. This might be improved by shorten the length of way of equipment.

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