在21世紀的今天，人類最主要的死亡原因仍是疾病及其所引發的器官壞死或衰竭，亦或是組織的功能喪失。目前對於這些喪失功能的組織，所能給予的治療方式主要只有器官移植與使用生醫材料替代物。然而這些方法都存在著許多缺點，若是能將這些組織於已修復，或是將之更新，便能提供一種新的治療方式。組織工程的重點在於修復或製造新的組織，以替換原有壞死的組織，組織工程分為三大要素，分別為細胞來源，細胞成長與分化因子，細胞支架，彼此缺一不可。
本實驗選用多孔性磷酸鈣鹽作為骨組織工程的細胞支架，磷酸鈣鹽具有生物相容性佳，且與骨組織的細胞外基質十分相似。骨組織中的細胞外基質約有70％（wt%）便是由磷酸鈣鹽所組成，另外30％為有機物，主要是膠原蛋白。實驗上發現多孔性磷酸鈣鹽的孔隙率，與孔洞大小，皆與骨組織再造時有密切關係。
實驗中利用各種不同的孔洞先驅物與磷酸鈣鹽混合，希望能找出較佳的孔洞先驅物，並且利用各種方法增加強度，並進行細胞毒性測試，希望能製造出較佳的骨組織工程支架。

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