近年來，隨著我國物聯網產業創新應用發展的推動及高齡化社會到來，需更加完善的遠端照護設備，也隨著微奈米材料及微機電科技發展的成熟，使元件可以微小化，讓相關應用可以蓬勃發展，如手機、輔具科技、檢驗醫學等方面，成為當下政府積極推動的明星產業，從產業經濟與趨勢研究報告中心的相關建言中，提到台灣智慧城市價值創造應從解決在地問題著手，而醫療照護社會成本過高是我國面臨社會問題裡的其中一項，俗話說：預防勝於治療，疾病早期發現早期治療通常有最佳療效，且有助於節省醫療資源及可廣泛應用於醫療保健用途；而以前疾病的篩檢主要是病灶在外觀上出現異常，例如：癌症患者組織明顯增生，再經由影像判讀時，通常已經是疾病中後期，所以由人體生理狀態下，正常應有的化學物質含量變化，當作判定原理的可快速篩檢的檢驗醫學儀器已是不可或缺的一角。本研究結合微機電製程技術與交流電動力可濃縮生物粒子的作用，使檢驗平台微小化、檢體減量及不需外加流體驅動力，具有可使檢驗時間縮短及方便攜帶的優點；根據我們實驗參數下得到的實驗結果來分析，本實驗晶片用來收集菌尿症中最常分離出的大腸桿菌，實驗結果顯示具很好的線性關係(R2= 0.99)，顯示所探討出來的水試樣前處理法可導入環狀指叉型電極晶片於尿液中細菌量之檢驗，將有助於菌尿症快速判知上的應用。

Bio-chips have recently emerged as a potential tool for detecting bio-particles such as bacteria, virus, DNA, RNA, and so on, with bio-chips using ACEO combined with P-DEP force of AC electro-kinetic force applied for separation or concentration of the materials of interest. The aim of this study was to investigate the efficacy of the rapid screening of bacteriuria by a Ring-shaped Interdigitated Electrode (RIDE). The fabrication procedure, sample preparation, and optimum experimental parameters of frequency and voltage for E. coli (ATCC25922) are discussed to examine the particle concentration efficiency. E. coli in healthy urine is used as a phantom to test the chip performance. The results showed that E. coli in healthy urine exhibited a linear relationship with time in the range of validity (R2＝0.99). This means that the method of aqua-sample pretreatment may be introduced into a Ring-Shaped Interdigitated Electrode Chip, with potential applications for screening out bacteriuria.

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