為了使紙張能作為良好之包裝材料以減少塑膠包裝的使用，需開發環保且抗菌之塗層以解決包裝紙之缺點。本實驗將具有良好奈米特性之奈米纖維素(cellulose nanocrystals, CNC)以高碘酸鹽氧化之方式將CNC醛化製作出二醛奈米纖維素(dialdehyde cellulose nanocrystals, DACNC)隨後與光敏劑赤蘚紅(Erythrosine)複合使其具有光動力殺菌(photodynamic inactivation, PDI)之效果，製作出CNC赤蘚紅複合材料(Ery-DACNC) 以達到功能化(functionalize)之目的，最後將此材料以浸塗法並配合逐層(layer by layer)之方式塗佈至牛皮紙(Kraft paper)上，製作出具有多功能塗層之複合塗層紙。
CNC經過醛化後其產量會隨著醛基含量增加而下降，且經由傅立葉轉換紅外線光譜 (Fourier Transform Infrared Spectrometer, FTIR)後確認其具有醛基之結構。與赤蘚紅複合後其FTIR光譜則新出現了羧酸根之特徵峰以及醛基之特徵峰產生減弱證明其利用醛基與赤蘚紅做複合，且複合量隨著赤蘚紅添加量增加而上升。殺菌效果以赤蘚紅添加量為100 mg且濃度為1.5 wt.%時之Ery-DACNC最佳，其在照射綠光30 min後能滅除90%以上之細菌且照射白光60 min後能滅除85%以上之細菌。經過塗佈後之塗層紙其性質隨著Ery-DACNC濃度及塗層數增加，最後選擇以4.5 wt.%之Ery-DACNC逐層塗佈15層做為最佳參數，經過塗層後之複合塗層紙其物理性質相比牛皮紙及PE淋膜紙皆有提升，且照射綠光40 min後能滅除90%以上之細菌而照射白光60 min後能滅除80%以上之細菌。

In this experiment, a new multi-function paper coating material was made in order to enhance the properties of paper to reduce the use of plastic packaging. An excellent natural nanomaterial cellulose nanocrystals (CNC) was used as coating substrate. CNC was functionalized by using periodate oxidation to turn CNC into dialdehyde cellulose nanocrystals (DACNC) and combined with photosensitizer Erythrosine, making photodynamic antibacterial cellulose nanocrystals coating material (Ery-DACNC). Ery-DACNC performed excellent photodynamic inactivation (PDI) ability with both green light and white light LED irradiation. Layer by layer dip coating process was used to coat Ery-DACNC on Kraft paper. After coating on Kraft paper, the Ery-DACNC coated paper performed better physical properties compared to uncoated paper and PE coated paper. The surface PDI ability of Ery-DACNC was also tested, the result showed that Ery-DACNC coated paper could performed excellent with both green light (excitation wavelength) and white light (simulate practical situations) LED irradiation.

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