本論文探討培養基之組成成份對於Streptococcus zooepidemicus ATCC 39920醱酵生產玻尿酸之影響。在本研究裡所探討的基礎培養基中含有20 g/L glucose、10 g/L yeast extract、2 g/L NaCl 和2.5 g/L K2HPO4。在這培養基中已經提供了足夠的Mg2+。不需再這培養基中額外添加Mg2+。以蔗糖取代葡萄糖。在培養基中補充tryptone 和soytone 能夠促進玻尿酸生產，並指出培養基中的混合氮源，對於玻尿酸醱酵是必要的。

The effect of medium composition on the production of hyaluronic acid by Streptococcus zooepidemicus ATCC 39920 was investigated in this study. The basal medium discussed in the study containing 20 g/L glucose, 10 g/L yeast extract, 2 g/L NaCl and 2.5 g/L K2HPO4. The medium composition containing 10 g/L of yeast extract could afford sufficient Mg2+. It is not necessary to add extra Mg2+ in the medium. Glucose can be replaced by sucrose. The supplementation of tryptone and soytone improved the production of hyaluronic acid indicating what the medium consisted of multiple nitrogen sources is essential for hyaluronic acid fermentation.

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