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研究生: 賽蔚雅
Setiawardhani, Widya Apriari Devita
論文名稱: 模擬探討粒子在微流道內電場及流場作用下之運動行為
Simulation of Particle Motion Induced by Electrokinetic and Hydrodynamic Flow Inside Microchannel
指導教授: 莊怡哲
Juang, Yi-Je
學位類別: 碩士
Master
系所名稱: 工學院 - 化學工程學系
Department of Chemical Engineering
論文出版年: 2011
畢業學年度: 99
語文別: 英文
論文頁數: 97
外文關鍵詞: Dielectrophoresis, Hydrodynamic flow, Drift-diffusion dynamics
相關次數: 點閱:81下載:2
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  • Dielectrophoresis is one of the major AC electrokinetic phenomena which has been widely demonstrated in microfluidics research as a method to control and manipulate micro and nano-scale particles in liquid. Predicting the movement and behavior of particles under non-uniform AC electric fields by numerical modeling and simulation is important for the design of experiment devices.
    In this study, we consider special conditions where the coupled dielectrophoresis (DEP) force and the hydrodynamic force contribute to the movement and behavior of particles in dielectrophoretic devices. Based on a drift-diffusion dynamics, we employ the Effective Medium Approximation (EMA) in order to include many particles in a system device. 2D simulation of mathematical model is adopted. We use two different channel geometry (non-rectangular and rectangular microchannel) and three different electrode arrangements (A, B and C) as a model device. In the first case we consider a microchannel with electrodes produce an AC electric field, filled with an incompressible and Newtonian suspending medium include many-particles within it. The second and the third case, the fluid and particles are introduced into the microchannel with and without an electric field applied, respectively.
    At certain point evaluation for each of the configuration (A, B and C) when only the electric field applied, the highest amount of particles trapped is observed at the electrode edges in configuration A where the particle volume fraction φ = 0.59, whereas in configuration B and C are φ=0.54 and φ=0.53, respectively. When the hydrodynamic flow coupled with electrostatic force, at fluid velocity 20 µm/s the highest amount of particles trapped is observed in configuration A φ=0.61, whereas in configuration B and C are φ=0.55 and φ=0.52, respectively. When rectangular microchannel is used, the highest amount of particles trapped is observed in configuration A φ=0.59, whereas in configuration B and C are φ=0.48 and φ=0.5, respectively. In addition, for configuration C only, when the electrode gap is decreased from 40 µm to 20 µm, the highest amount of trapped particles observed is φ=0.62.
    In conclusions, the geometry of the electrodes has significant effect on the DEP force and hence the particles motion. Moreover, the presence of the fluid flow affects the amount of particles trapped.

    List of Contents Abstract i Acknowledgement iii List of Contents v List of Tables viii List of Figures ix Chapter 1 Introduction 1 1.1 Research Background 1 1.2 Objectives 2 Chapter 2 Literature Review 4 2.1 Electrokinetics 4 2.2 AC Electrokinetics Theory 5 2.2.1 Dielectrophoresis 5 2.2.2 The induced effective dipole moment of a particle : Clausius Mossotti Factor 8 2.2.3 Forces on an induced dipole : Dielectrophoresis (DEP) in an AC field 10 2.3 Fluid Dynamics 13 2.3.1 Fluid flow : The Navier Stokes Equation 13 2.3.2 Steady state dielectrophoresis 13 2.4 Drift-diffusion dynamics 14 2.4.1 Effective medium approximation (EMA) 16 Chapter 3 Modeling and Numerical Methods 17 3.1 Introduction to COMSOL Multiphysics 17 3.2 Modeling in COMSOL Multiphysics 18 3.3 Model definition 20 3.4 Simulation process 22 3.4.1 Geometry modeling 22 3.4.1 Modeling physics and equation 24 3.4.1.1 Effective Medium Approximation (EMA) 24 3.4.1.2 Electrostatics part 25 3.4.1.3 Forces acting on particle 26 3.4.1.4 Drift-diffusion dynamics 27 3.4.1.5 Hydrodynamics part 28 3.5 Analysis of simulation results 29 Chapter 4 Results and Discussion 30 4.1 Frequency response of Clausius Mossotti factor 30 4.2 Simulation of electrical field distribution 33 4.2.1 Electrical field distribution for configuration A 33 4.2.2 Electrical field distribution for configuration B 35 4.2.3 Electrical field distribution for configuration C 36 4.3 Particle distribution induced by electrostatic field 37 4.3.1 Particle distribution for configuration A 39 4.3.2 Particle distribution for configuration B 40 4.3.3 Particle distribution for configuration C 41 4.4 Particle distribution induced by hydrodynamic field 42 4.5 Particle distribution induced by hydrodynamic and electrostatic field 47 4.5.1 Effect of hydrodynamic in conjunction with electrostatic force 47 4.5.1.1 Particle distribution for configuration A 47 4.5.1.2 Particle distribution for configuration B 53 4.5.1.3 Particle distribution for configuration C 58 4.5.2 Effect of channel geometry 64 4.5.2.1 Rectangular microchannel 64 4.5.2.2 Small electrode gap 81 Chapter 5 Conclusions 89 Chapter 6 Future Works 91 References 92

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