簡易檢索 / 詳目顯示

研究生: 黃書瑋
Huang, Shu-Wei
論文名稱: 具交錯T形截面之微混合器中的流體混合
Mixing of fluids in a micromixer with staggered T-shaped cross-sections
指導教授: 吳志陽
Wu, Chih-Yang
學位類別: 碩士
Master
系所名稱: 工學院 - 機械工程學系
Department of Mechanical Engineering
論文出版年: 2014
畢業學年度: 102
語文別: 中文
論文頁數: 186
中文關鍵詞: 微流體力學混合器T形截面田口法縱向渦流
外文關鍵詞: microfluidics, mixer, T-shaped cross-section, Taguchi method, longitudinal vortex
相關次數: 點閱:99下載:2
分享至:
查詢本校圖書館目錄 查詢臺灣博碩士論文知識加值系統 勘誤回報
  • 本文提出一種使不同流體由兩入口注入具交錯T形截面之主流道的微混合器。首先,利用數值模擬軟體CFDRC模擬各流道段排列的混合情況,並找出其中有較佳混合效果的流道段排列方式,為了方便,我們使用代號A、B及C分別表示偏右的T形截面流道段、偏左的T形截面流道段及方形截面流道段。接著,利用田口法找出較佳的第一T形截面流道段長度(la)、第二T形截面流道段長度(lb)、方形截面流道段長度(lc)及流道內的模組排列方式,並分析各參數在Re = 0.01~10對混合的影響。為了驗證數值模擬是否可靠,使用微影技術製作微混合器,並利用雷射共軛焦顯微鏡擷取流體在微混合器中的混合影像,由模擬與實驗結果相比較,發現兩者相當一致。本文結果顯示:(一)流體在低雷諾數(Re ≤ 10)下依序流經偏右與偏左T形截面流道段後,會產生縱向渦流,且此渦流在接下來的方形截面流道段會持續存在並增進混合效果。(二)參數對混合度的影響由大到小依序排列為:流道內截面排列方式,第二T形截面流道段長度,方形截面流道段長度,第一T形截面流道段長度。(三)改變方形截面流道段長度與流道內的截面排列方式,幾乎不會影響壓降大小,而改變第一T形截面流道段長度與第二T形截面流道段長度,雖會影響壓降大小,但影響不大。(四)在低雷諾數(Re ≤ 10)時,具交錯T形截面之微混合器的參數以la = 0.75Wm、lb = Wm、lc = 0.75Wm (Wm代表主流道的寬度)及12個模組中皆為ABC的排列順序時的混合效果為最佳。

    We propose a micromixer which allows two different fluids to flow into the main channel consisting of modular subsections with staggered T-shaped cross-sections. The simulation results obtained by the software, CFDRC, show the following trend. When mixing fluid flows into a T-shaped cross-section subsection with center moved to the right (represented by symbol A) and a following T-shaped cross-section subsection with center moved to the left (represented by symbol B), a longitudinal vortex is induced. The vortex persists in the following square cross-section subsection (represented by symbol C) and enhances mixing for the case with a small Reynolds number (≤ 10). Next, we fabricate the micromixer by photolithography and apply a confocal microscopy to acquire the mixing flow images. The comparisons of the simulation results and the images show qualitative agreement. Finally, we adopt the Taguchi method to select better parameters, including the length of the first and the second T-shaped cross-section subsection (la and lb), that of the square cross-section subsection (lc) and the arrangement of modules. The simulation based on the Taguchi method shows that the effectiveness of the parameters is ranked as: the arrangement of modules > lb > lc > la and the mixing efficiency of the micromixer with la = 0.75Wm, lb = Wm, lc = 0.75Wm (with Wm denoting the main channel width) and the staggered cross-sections of each of the twelve modules arranged in the order of A, B and C is higher than that of the other similar micromixers.

    摘要 I Abstract II 誌謝 VIII 目錄 IX 表目錄 XII 圖目錄 XIII 符號說明 XXX 第一章 緒論 1 1-1 研究背景 1 1-2 文獻回顧 1 1-3 研究動機 3 1-4 本文架構 4 第二章 理論與數值模擬 5 2-1 微混合器設計與模擬概述 5 2-2 基本假設 6 2-3 統御方程式 6 2-4 邊界條件 7 2-5 無因次化 7 2-5-1 方程式的無因次化 7 2-5-2 邊界條件的無因次化 8 2-6 數值模擬 9 2-6-1 CFD-GEOM 建立流道幾何形狀與網格 9 2-6-2 CFD-ACE+ 模擬運算 9 2-6-3 CFD-VIEW 做後處理 10 2-7 混合度 10 第三章 應用田口法之微混合器設計 11 3-1 微混合器外形簡介 11 3-2 微混合器外形排列方式 11 3-3 田口法 12 3-4 最佳化流道設計 13 第四章 微混合器製作與實驗觀測 15 4-1 微混合器之製作流程 15 4-1-1 光罩設計 15 4-1-2 母模製作 15 4-1-3 表面粗度儀量測光阻高度 17 4-1-4 翻模製作微混合器上蓋 18 4-1-5 微混合器上下蓋貼合與管線黏合 18 4-2 實驗觀測 18 4-2-1 工作流體與微量式注射幫浦 18 4-2-2 實驗影像擷取 19 第五章 結果與討論 20 5-1 簡介 20 5-2 微混合器中各種截面流道段排列組合之流動與混合比較 20 5-3 網格測試 21 5-4 模擬與實驗結果之比較 22 5-5 最佳化流道之流動與混合情況 22 5-5-1 雷諾數0.01、0.04、0.125、0.354的流動與混合現象 24 5-5-2 雷諾數1、3.162、10的流動與混合現象 25 5-5-3 最佳化流道綜合討論 26 5-6 各種Re下,各幾何參數對流動與混合效能的影響 26 5-6-1 la對流動、混合效能及壓降的影響 26 5-6-2 lb對流動、混合效能及壓降的影響 28 5-6-3 lc對流動、混合效能及壓降的影響 30 5-6-4 流道內的模組排列方式對流動、混合效能及壓降的影響 32 第六章 結論與未來展望 34 6-1 結論 34 6-2 未來展望 35 參考文獻 36

    1. A. Manz, N. Graber, H. M. Widmer, “Miniaturized total chemical analysis system: a novel concept for chemical sensing,” Sensors and Actuators, B, vol. 1, pp. 244-248, 1990.
    2. L. Capretto, W. Cheng, M. Hill, and X. L. Zhang, “Micromixing within microfluidic devices,” Microfluidics: Technologies and Applications, vol. 304, pp. 27-68, 2011.
    3. L. H. Lu, K. S. Ryu, and C. Liu, “A magnetic microstirrer and array for microfluidic mixing,” Journal of Microelectromechanical Systems, vol. 11, pp. 462-469, 2002.
    4. I. Glasgow, N. Aubry, “Enhancement of microfluidic mixing using time pulsing,” Lab on a Chip, vol. 3, pp.114-120, 2003.
    5. A. O. El Moctar, N. Aubry, and J. Batton, “Electro-hydrodynamic micro-fluidic mixer,” Lab on a Chip, vol. 3, pp. 273-280, 2003.
    6. H. H. Bau, J. H. Zhong, and M. Q. Yi, “A minute magneto-hydro-dynamic (MHD) mixer,” Sensors and Actuators, B, vol. 79, pp. 207-215, 2001.
    7. R. H. Liu, J. N. Yang, M. Z. Pindera, M. Athavale, and P. Grodzinski, “Bubble-induced acoustic micromixing,” Lab on a Chip, vol. 2, pp. 151-157, 2002.
    8. J.-H. Tsai, L. Lin, “Active microfluidic mixer and gas bubble filter driven by thermal bubble micropump,” Sensors and Actuators, A, vol. 97-98, pp. 665-671, 2002.
    9. P. Löb, K. S. Drese, V. Hessel, S. Hardt, C. Hofmann, H. Löwe, “Steering of liquid mixing speed in interdigital micro mixers - from very fast to deliberately slow mixing,” Chemical Engineering and Technology, vol. 27, pp. 340-345, 2004.
    10. R. Miyake, T. S. J. Lammerink, M. Elwenspoek, J. H. J. Fluitman, “Micro mixer with fast diffusion,” IEEE MEMS, pp. 248-253, 1993.
    11. J. Voldman, M. L. Gray, and M. A. Schmidt, “An integrated liquid mixer/valve,” Journal of Microelectromechanical Systems, vol. 9, pp. 295-302, 2000.
    12. H. Song, M. R. Bringer, J. D. Tice, C. J. Gerdts, and R. F. Ismagilov, “Experimental test of scaling of mixing by chaotic advection in droplets moving through microfluidic channels,” Applied Physics Letters, vol. 83, pp. 4664-4666, 2003.
    13. A. Günther, M. Jhunjhunwala, M. Thalmann, M. A. Schmidt, and K. F. Jensen, “Micromixing of miscible liquids in segmented gas-liquid flow,” Langmuir, vol. 21, pp. 1547-1555, 2005.
    14. A. D. Stroock, S. K. W. Dertinger, A. Ajdari, I. Mezic, H. A. Stone, and G. M. Whitesides, “Chaotic mixer for microchannels,” Science, vol. 295, pp. 647-651, 2002.
    15. A. D. Stroock, S. K. Dertinger, G. M. Whitesides, and A. Ajdari, “Patterning flows using grooved surfaces,” Analytical Chemistry, vol. 74, pp. 5306-5312, 2002.
    16. J. T. Yang, W. F. Fang, and K. Y. Tung, “Fluids mixing in devices with connected-groove channels,” Chemical Engineering Science, vol. 63, pp. 1871-1881, 2008.
    17. 林雨欣, “具溝槽之波紋形微混合器中的流體混合,” 國立成功大學機械工程研究所碩士論文, 2011.
    18. D. S. Kim, S. W. Lee, T. H. Kwon, and S. S. Lee, “A barrier embedded chaotic micromixer,” Journal of Micromechanics and Microengineering, vol. 14, pp. 798-805, 2004.
    19. J. M. Park, K. D. Seo, and T. H. Kwon, “A chaotic micromixer using obstruction-pairs,” Journal of Micromechanics and Microengineering, vol. 20, 2010.
    20. S. A. Rani, B. Pitts, P. S. Steward, “Rapid diffusion of fluorescent tracers into Staphylococcus epidermidis biofilms visualized by time lapse microscopy,” Antimicrobial Agents Chemotherapy, vol. 49, pp. 728-732, 2005.
    21. J. Boss, “Evaluation of the homogeneity degree of mixture,” Bulk Solids Handling, vol. 6, pp. 1207-1215, 1986.

    下載圖示 校內:2019-08-20公開
    校外:2019-08-20公開
    QR CODE